Southern California's
Tech
Startup Directory
Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.
Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Does business as ChipAgents, an agentic AI chip-design platform founded by CEO William Wang; has raised $134M in funding from investors including Bessemer Venture Partners and Matter Venture Partners.
Series A$73.6MWe’re an integrated photonics company in California building the light engines that power the next era of quantum technology — from advanced computing to precision sensing.
$73.4MAI search/advertising company (ProRata.ai) backed by Touring Capital, Mayfield Fund, and Revolution Ventures; has raised more than $75M total, including a $40M Series B in September 2025.
Gene therapy company that emerged from stealth in June 2023 with a $51M Series A co-led by Westlake Village BioPartners, developing AAV-based genetic medicines for muscle and heart disease.
Seed$71.0MEnigma is a physical AI startup building an intelligence layer for the robotics industry.
Series B$67.6MThis is the legal entity behind Liquid Death, the canned-water brand founded by Mike Cessario in 2019; its backers have included Live Nation and celebrity investors such as Josh Brolin.
$67.1MLegal name of Flip, the TikTok-style social shopping app headquartered in El Segundo, CA; the company raised $144M and reached a $1B valuation before shutting down in August 2025.
Series A$63.3MCo-founded by biomedical engineer Robert S. Hillman, PhD; developing devices/therapies to get STEMI heart-attack patients to treatment with open coronary arteries, and has raised $58.4M.