Southern California's
Tech
Startup Directory
Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.
Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series B$10.1MThe collective brain for high-velocity teams. Join waitlist: highlightai.com
Series B$10.0MFounded by CEO Brandon Werber, airVet has raised over $40M in venture funding, including a Series B-2 round led by HighlandX and HighPost Capital.
Series B$10.0MAvicena was founded in 2019 by Bardia Pezeshki and raised a $65M Series B led by Tiger Global with participation from SK Hynix and Prosperity7 Ventures.
Series B$10.0MTopicals is transforming the way you feel about skin through effective science backed products for chronic skin conditions and mental health advocacy.
Series B$9.4MMucho Mas Media is an independent studio that empowers and supports the stories of Latino communities and filmmakers through its global production, financing, and distribution capabilities.
Series B$9.0MReplacing Hearts. Restoring Lives. HEART FAILURE Heart failure is a global epidemic affecting at least 26 million people worldwide, 6.2 million adults in the U.S., and is increasing in prevalence. Heart transplantations are reserved for those with severe heart failure and
Series B$9.0MLuxury haircare and tools that turn everyday routines into meaningful rituals, helping support healthier hair with ease and intention.
Series B$8.3MMSI is the single platform for medical device cybersecurity compliance — tools, data, and expert support to meet FDA requirements and ship on schedule. 100% FDA approval rate.