Southern California's
Tech
Startup Directory
Showcasing Southern California's innovation, one startup at a time. Every funded and bootstrapped company, from seed round to first dollar of revenue, tracked as it happens.
Includes SEC Form D filings from the last 3 years, plus all-time totals for companies sourced from YC and news coverage.
Artificial Intelligence
The region's largest single cluster by company count — AI and machine learning threaded through nearly every other industry here, from defense to biotech to entertainment.
Aerospace & Defense
Home to SpaceX, Northrop Grumman, and a new wave of hypersonics and space-infrastructure startups.
Entertainment & Gaming Tech
Hollywood's production infrastructure, live events, and a growing games and creator-tools scene.
Semiconductor Hardware
Qualcomm and Broadcom anchor a chip-design cluster spanning the region.
Medical Technology
A deep biotech research base and a growing bench of medical device and diagnostics startups.
B2B
Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.
Industrials
Manufacturing, hardware, and physical-world operations. Overlaps heavily with the region's decades-old aerospace and defense manufacturing base, now extending into robotics and automated production.
Consumer
Products and apps built directly for individual consumers, drawing on Southern California's media and entertainment base.
Healthcare
Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Fintech
Financial technology: payments, banking, investing, and financial infrastructure.
Education
Education technology and learning platforms built across Southern California.
Real Estate & Construction
Property technology, construction tech, and real estate services.
Series B$16.5MElectrolytes formulated with premium, all-natural and organic ingredients. Instant Hydration replenishes you faster and longer than water alone.
Series B$16.4MIrvine-based Mixed-Signal Devices was founded by Avi Madisetti (CEO) and Tommy Yu and has raised roughly $26.8M, with Kyocera Ventures among its investors.
Series B$15.8MAn integrated communications platform using cloud-hosted phone, chat, contact center and analytics to meet the challenges of today’s business.
Series B$15.6M
Series B$15.5MSyndex Bio was founded by Geoff Smith and raised a $15.5M seed round backed by ARCH Venture Partners, one of the top-tier biotech venture firms.
Series B$15.2MThe Data Intelligence Network for Healthcare OutcomeMD’s Patient Experience Data Network™ turns de-identified patient-reported outcome measures (PROMs) into act
This Carlsbad, CA private-equity vehicle for engineered stone manufacturing is run by managing member Oren Klaff, the investor and author best known for the bestselling sales book "Pitch Anything."
Series B$15.0MPrimrose Bio specializes in innovative manufacturing solutions for biotherapeutics and vaccines, setting new standards for quality and production efficiency.