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B2B startups in Southern California

Business software and services sold to other companies. The largest single category of startup across Southern California, spanning sales tools, vertical operating systems, and everything in between.

It's the largest category here by far, and one of the most varied — the best-funded names span Shield AI's defense-focused autonomy software in San Diego, Metropolis Technologies' AI-powered parking infrastructure in Santa Monica, and Impulse Space's in-space transportation services in El Segundo. What ties them together isn't a shared product category, just a shared buyer: another business, not a consumer.

1030
companies
$20.56B
total raised
62
cities

Companies

Seed$9.4M
Delphi Interactive LLC
Beverly Hills, CA

Delphi builds AAA games based on the most desirable IP franchises in the world

SeedB2B
Verses AI Inc. hero photo
Seed$9.4M
Verses AI Inc.
Los Angeles, CA · Founded 2020

Enterprise AI for finance that thinks and learns like people. VERSES Genius™ is used to manage risk when data is volatile, uncertain, complex & ambiguous.

SeedB2B
Seed$9.4M
TINWELL LABS INC.
Covina, CA · Founded 2022

Tinwell Labs is the legal entity behind Era, an AI-powered wealth management platform co-founded by Alex Norcliffe and Lindsay Brady that has raised roughly $9.4M in funding.

SeedB2B
Series A$9.3M
EVERVERSE INC.
Huntington Beach, CA · Founded 2022
Series AB2B
$9.2M
OCG Litigation Portfolio LLC
Anaheim, CA · Founded 2025
B2B
Permissionless Labs, Inc. hero photo
Series A$9.2M
Permissionless Labs, Inc.
Irvine, CA · Founded 2021 · ~11-50 employees

Permissionless Labs is an AI lab providing high-throughput inference, durable model storage, and custom fine-tuning — frontier infrastructure you can access without gatekeepers or lock-in.

Series AB2B
$9.1M
Active Entertainment Texas, LLC
Costa Mesa, CA · Founded 2024

Active Entertainment Texas, LLC provides event planning, film & live production, and event rental services for schools, corporate events, and weddings.

B2B
Incite Inc hero photo
Series A$9.1M
Incite Inc
Los Angeles, CA · Founded 2023 · ~11-50 employees

Incite is a venture capital firm that invests in entrepreneurs, provides grants to non-profit organizations, and funds initiatives aimed at changing politics.

Series AB2B
BiVACOR Inc. hero photo
Series B$9.0M
BiVACOR Inc.
Huntington Beach, CA

Replacing Hearts. Restoring Lives. HEART FAILURE Heart failure is a global epidemic affecting at least 26 million people worldwide, 6.2 million adults in the U.S., and is increasing in prevalence. Heart transplantations are reserved for those with severe heart failure and

Series BB2B
Mitra EV, Inc. hero photo
Seed$9.0M
Mitra EV, Inc.
Redondo Beach, CA · Founded 2023

Discover sustainable solutions for your fleet with Mitra EV. Our comprehensive electric fleet solutions offer businesses a seamless transition to cleaner, cost-effective transportation

SeedB2B
Seed$9.0M
General Galactic Technologies Corp
El Segundo, CA · Founded 2023

General Galactic builds advanced spacecraft for sustained maneuver and more time on-mission across the space domain

SeedB2B
Cognixion Corp hero photo
Seed$8.9M
Cognixion Corp
Santa Barbara, CA · Founded 2021

Cognixion develops accessible, non-invasive brain-computer interfaces combining neuroscience, AI, and spatial computing.

SeedB2B
Series A$8.8M
STYNGR CORP.
Santa Monica, CA · Founded 2020 · ~11-50 employees

STYNGR makes in-game audio seamless with easy SDK integration and flexible monetization options. Elevate your game with fully licensed music from major labels and indie artists.

Series AB2B
$8.8M
Aveera Medical Inc.
San Clemente, CA · Founded 2020
B2B
Seed$8.8M
HypeVR
San Diego, CA

HypeVR built cinematic volumetric VR capture technology using a 14-camera 6K rig, founded in San Diego in 2015.

SeedB2B
Series A$8.5M
Luxvitae Therapeutics Inc.
San Diego, CA
Series AB2B
Sonocharge Energy, Inc. hero photo
Series A$8.5M
Sonocharge Energy, Inc.
San Diego, CA · Founded 2022

A piezoacoustic platform technology that makes the world’s batteries last longer, charge faster, and be safer.

Series AB2B
Series A$8.5M
Small Molecules Inc.
Santa Monica, CA · Founded 2021

SmallMolecules.com provides the largest listing of commercially-available small molecule products, assisting researchers to find the products they need to drive discovery.

Series AB2B
EdgeX, Inc. hero photo
Series A$8.5M
EdgeX, Inc.
San Diego, CA · ~11-50 employees

Get instant real-time visibility with EdgeX. Wire-free RTLS, asset tracking, and environmental monitoring. Fast ROI, no IT burden, deployed in hours.

Series AB2B
$8.4M
Cre8tech Labs, Inc.
Pasadena, CA

Cre8tech Labs does business as Lender Price, a mortgage fintech that received a strategic investment from Regions Bank in 2018.

B2B
Inertia Systems, Inc. hero photo
Seed$8.3M
Inertia Systems, Inc.
Chula Vista, CA · Founded 2019

Transform job-site drawings into actionable tools for tracking every building element from day one.

SeedB2B
Jeeva AI, Inc. hero photo
Series A$8.3M
Jeeva AI, Inc.
Santa Monica, CA

Build, deploy, and govern autonomous digital workers across revenue, IT, service, and operations. Automate workflows, execute tasks, and scale work with AI-powered digital workers.

Series AB2B
Series B$8.3M
MedCrypt Inc.
Solana Beach, CA

MSI is the single platform for medical device cybersecurity compliance — tools, data, and expert support to meet FDA requirements and ship on schedule. 100% FDA approval rate.

Series BB2B
Series A$8.2M
Zuub, Inc.
Culver City, CA · Founded 2019

Zuub provides insurance verification infrastructure for dental, offering a Dental Insurance Eligibility & Benefits API to turn complex payer information into reliable, product-ready data for applications.

Series AB2B
Series C$8.2M
SAIL FUSION, LLC
Del Mar, CA
Series CB2B
Series A$8.2M
4600 NVDT LLC
Irvine, CA · Founded 2025
Series AB2B
$8.2M
CU DIRECT CORP
Irvine, CA · ~501-1,000 employees

CU Direct Corp, founded in 1994 and now branded as Origence, is a credit union service organization (CUSO) collectively owned by 124 credit union shareholders rather than by venture investors.

B2B
Rasa World Group, Inc. hero photo
Series B$8.2M
Rasa World Group, Inc.
West Hollywood, CA · Founded 2023

Rasa World Group, Inc. provides an all-in-one ecosystem of software and creative services to build, scale, and operate global events and experiences.

Series BB2B
$8.1M
Seaboard Assets Corp.
Costa Mesa, CA

Seaboard Corporation manages every aspect of its business from farms and processing plants to container shipping and commodity trading, with roots in grain and agriculturally derived products.

B2B
Fortastra Corp hero photo
Seed$8.1M
Fortastra Corp
Torrance, CA · Founded 2025

Orbital defense built for scale.

SeedB2B
Outer Spaces, Inc. hero photo
Series A$8.0M
Outer Spaces, Inc.
Los Angeles, CA · Founded 2025

OUTERSPACES INC. PHILADELPHIAS PREMIER DESIGNER AND BUILDER OF LANDSCAPE ARCHITECTURAL ELEMENTS, SWIMMING POOLS, FOUNTAINS, AND OUTDOOR LIVING SPACES.

Series AB2B
Topanga.io Corp. hero photo
Series A$7.7M
Topanga.io Corp.
Los Angeles, CA · Founded 2021 · ~11-50 employees

We build kitchen intelligence tools to cut food waste, eliminate single-use packaging and optimize resources across every stage of food production.

Series AB2B
$7.6M
PointOne Elise AI LLC
Manhattan Beach, CA · Founded 2025

EliseAI is the industry-leading AI platform transforming both property management and healthcare through automation and conversational AI that help housing and healthcare organizations streamline communications and improve operational efficiency.

B2B
H2 Clipper, Inc. hero photo
Series A$7.6M
H2 Clipper, Inc.
Santa Barbara, CA · Founded 2022

The infrastructure for the distribution of liquid hydrogen.

Series AB2B
Ezra Climate Inc. hero photo
Seed$7.6M
Ezra Climate Inc.
Covina, CA · Founded 2024

Ezra Climate was founded by Dan Rosen and Dori Rutkevitz, who previously helped scale Mosaic, a solar fintech platform that financed over $15B in projects; Ezra raised an $8M seed round for AI infrastructure serving private capital markets.

SeedB2B
$7.5M
LTHS, Inc.
San Clemente, CA · Founded 2025
B2B
Talino Ventures PBC hero photo
Series A$7.5M
Talino Ventures PBC
Manhattan Beach, CA

Talino Fintech Foundry helps technology platforms and enterprises launch secure and compliant fintech products faster with MCP-ready and API-enabled infrastructure.

Series AB2B
$7.5M
EV-PETROL INC
Lake Forest, CA · Founded 2024
B2B
Series A$7.5M
4UNIQUENESS INC
Santa Monica, CA · Founded 2023
Series AB2B
STELLAR DESIGNS hero photo
Series C$7.5M
STELLAR DESIGNS
Santa Ana, CA

Stellar Designs, Inc. offers unique, quality promotional products and branding solutions from its office in Anchorage, Alaska.

Series CB2B
BUNDY INVESTMENTS INC hero photo
$7.5M
BUNDY INVESTMENTS INC
Los Angeles, CA · Founded 2024

Discover Bundy Group’s expert investment banking and advisory services, helping business owners achieve growth, strategy, and successful transactions.

B2B
Seed$7.5M
PointOne Family Office, LLC
Manhattan Beach, CA · Founded 2025

PointOne Family Office is a Manhattan Beach-based boutique multi-family office and SEC-registered investment adviser managing roughly $327M in assets.

SeedB2B
Series A$7.5M
DIMER INSTRUMENTS, INC.
Santa Barbara, CA · Founded 2023

Dimer Instruments creates instruments that enable real-time molecular analysis at multiple points during the pharmaceutical development process.

Series AB2B
Series A$7.5M
HGF TECHNOLOGIES NETWORK INC
Newport Beach, CA · Founded 2023
Series AB2B
PACE NEWS, INC. hero photo
$7.4M
PACE NEWS, INC.
Los Angeles, CA · ~11-50 employees

Pace News provides breaking news, local news for areas like Inglewood and California, business, health, education, politics, community, law enforcement, lifestyles, and arts & entertainment.

B2B
Series A$7.4M
Corner Health Platform, Inc.
Santa Monica, CA · Founded 2024

Find an independent primary care provider near you who takes your insurance and has real time to listen. Same-day, evening, and Saturday visits in AZ & WA.

Series AB2B
Tactiq Inc. hero photo
Series A$7.3M
Tactiq Inc.
Covina, CA · Founded 2020

Transcribed live. Summarised instantly. Tactiq captures every meeting in real time, so you walk out with notes, action items, and summaries ready. Trusted by 1 million users.

Series AB2B
Series B$7.3M
Provisio Medical, Inc.
San Diego, CA
Series BB2B
Seed$7.3M
Koobz, Inc.
Ventura, CA · Founded 2023

Koobz, Inc. manufactures custom footwear on-demand with zero inventory, allowing brands to launch their own original shoe designs.

SeedB2B
Seed$7.3M
Automotus
Los Angeles, CA

Curb management for cities, airports and fleets. Real-time data. Automated payments. Smart loading zones. Zero emissions delivery zones.

SeedB2B
Series A$7.3M
bioProtonics, Inc.
Santa Barbara, CA · Founded 2018

BioProtonics is a pioneering company focused on advancing diagnostic imaging through its Magnetic Resonance Histopathology (MRH) technology. MRH offers a non-invasive, high-resolution method for analyzing tissue microarchitecture during routine MRI scans. MRH

Series AB2B
$7.2M
LifeLine Series X SPV LLC
Beverly Hills, CA · Founded 2025
B2B
Stell Engineering, Inc. hero photo
Seed$7.2M
Stell Engineering, Inc.
Marina Del Rey, CA · Founded 2022

AI-native requirements management for engineers managing mission-critical compliance. Replace scattered docs and manual traceability with a single, audit-ready platform

SeedB2B
PeakMetrics, Inc. hero photo
Series A$7.2M
PeakMetrics, Inc.
Los Angeles, CA

Detect, decipher, and defend against coordinated narratives with PeakMetrics narrative intelligence.

Series AB2B
Live Data Technologies, Inc. hero photo
Series A$7.1M
Live Data Technologies, Inc.
Santa Barbara, CA · Founded 2019

Live Data Technologies provides live human capital data, including job-change data on professionals, re-verified and compliantly sourced from the open web.

Series AB2B
Flight Science, Inc. hero photo
Seed$7.0M
Flight Science, Inc.
West Hollywood, CA · Founded 2024

Achieve 30% turbulence reduction, $43 average fuel savings per flight, and 4s alert response times.

SeedB2B
$7.0M
Fineline Capital, LLC
Los Angeles, CA · Founded 2026
B2B
$7.0M
Fluxnium, Inc.
Santa Monica, CA · Founded 2026

Fluxnium's founder and CEO, Jeff Green, previously co-founded Stamps.com in 1996 with Jim McDermott (also a Fluxnium board member) and Ari Engelberg; Green also co-founded Rusheen Capital Management.

B2B
Clout Kitchen Holdings Inc. hero photo
Seed$7.0M
Clout Kitchen Holdings Inc.
Los Angeles, CA · Founded 2026

Distribution marketing for music, entertainment, gaming, and brands. The AI Engine for virality, generating millions of views monthly.

SeedB2B
JenZ Inc. hero photo
Seed$6.9M
JenZ Inc.
Santa Monica, CA · Founded 2019

Jenz is an internal social network that functions as a mobile intranet and an employee engagement app, aiming to transform internal organizational communication and boost company culture.

SeedB2B