B2B startups in Southern California

Transforming Biomanufacturing Through Nanofiber Technology Cellevat3d® VAX microcarriers redefine viral vaccine production with >10-fold higher yields

Founded by Wharton MBA Paul Dohrenwend; its premium sake made its retail debut at a Costco in San Diego.

Scientia Capital Management empowers retail investors with AI-powered investing, wealth management, and investment analysis. Smarter, risk-aware strategies for confident growth.

At Dream Management, all of our transportation services are personalized, catering to the unique challenges of your business.

TeaLink, Inc. is a community-driven digital platform that serves as a unified hub for diaspora communities, starting with the Persian/Iranian community, offering features such as event discovery, business directories, and housing listings.

Track shared bills all month, approve them together, and settle each month-end to build a portable reputation that travels with you.

Gino Pinto Inc. provides winemaking equipment, winemaking supplies, and wine grapes and juices from world-renowned growers.

TurboPermit helps residential builders and developers cut permit approval time by up to 50% with AI plan pre-check, digital forms, and one source of truth. Book a demo.

Growing profitable ecommerce brands since 2014

CityStructure, based in Walnut, CA, was founded by Felicia Nitu and built a real estate 'Development Score' tool for evaluating property development potential; the company has since rebranded as InstaDev.

AccessStar empowers independent and meaningful lives for people with intellectual or developmental disabilities by providing various behavioral and developmental services such as group homes, community engagement, and nursing care.

Ai DataFrames develops AI-driven prediction models that analyze global financial data and provide predictive intelligence for the top 16 Futures markets, aiming to predict days of high market imbalance.

Objectively Good Media helps purpose-driven brands communicate the value of their values through videos, websites, and webinars.

Craitor builds the production layer for critical hardware, deployed where it is needed, aiming to manufacture sovereignty.

Integrity is a company that uses AI-powered technology, data, and human touch to deliver insurance, financial, and investment advisory services.

MAPLE FUNG MD INC provides biotech consulting services, including fractional CMO roles and protocol design, and also offers per diem nephrology care and serves as a clinical trial investigator.

Influsence, Inc. provides an AI SaaS platform that offers data insights for influencer marketing to help increase reach, engagement, and revenue for ad agencies and companies.

Footprint Ventures Lab, Inc. invents technology at the intersection of data, computing, and decentralization.

Thegobo.com offers a wide range of gobos and LED projectors for industrial, corporate, entertainment, and consumer needs for projected images, including custom and stock gobos, virtual signs, and indoor and outdoor projectors.

Multi-model AI with a patent-pending AI Firewall — for teams where data privacy is not optional. 47 models, one workspace, sensitive data stays home.

Opticore builds photonic AI inference chips and is co-founded by CEO Zaijun Chen and CTO Ryan Hamerly, a former MIT research scientist; backers include Sagax Capital, Neotribe Ventures, and Origin Ventures.

Greenridge Realty is a real estate firm operating in West Michigan that assists with buying and selling homes, property management, and relocation services, and is a member of Leading Real Estate Companies of the World®.

Genesis LA is a Community Development Financial Institution (CDFI) and Community Development Entity (CDE) that delivers financial solutions to advance economic and social opportunities in underserved communities in Los Angeles.

Condor is an AI-powered platform that unifies clinical, operational, and financial data into a single source of truth for life sciences companies to manage R&D finances.

HONK provides an AI-powered platform for roadside assistance, specialized vehicle services, accident management, vehicle logistics, and catastrophe event management.

Bienestar Human Services provides full-service medical care, HIV/AIDS treatment and prevention, sexual health, mental health, substance use counseling, and medication-assisted treatment, alongside community services like men's health, trans health, harm reduction, youth empowerment, emergency housing, and food bank services.

Talino Fintech Foundry helps companies build and scale global financial products faster, more securely, and at lower cost by removing regulatory friction, enabling interoperability, and modernizing traditional finance with compliant stablecoin infrastructure on a unified platform.

Ember LifeSciences applies proprietary heating and cooling technology to the healthcare industry, offering self-refrigerated, cloud-based shipping boxes called Ember Cubes.

Fusion Capital Partners is a Los Angeles-based private equity firm that invests in engineered products and essential services businesses across the commercial and industrial markets of North America.

Stic connects advertisers with drivers to turn everyday vehicles into measurable media through campaign planning, live tracking, and reporting for out-of-home advertising.

Vital Lyfe is a tech company that develops personal water purification technology designed to take any naturally occurring water, including saltwater, and produce clean water.

AMAG Technology develops integrated physical security solutions that include identity management, access control, video management, mobile credentials, and visitor management.

Mirai Labs provides models, runtime, and infrastructure to make on-device AI interactive, ambient, and continuous, specifically co-designing models and runtime for Apple Silicon.

PureSpectrum offers a research marketplace for modern sampling to launch and manage global sample for global research programs.

Anchr provides AI agents for physical operations in industries such as food distribution, industrial and MRO, healthcare and pharma, building and technical supplies, and consumer packaged goods.

Synergetics.AI offers a trusted agentic infrastructure platform that allows AI agents to identify, communicate, and transact securely across enterprise boundaries.

PADO offers AI orchestration solutions for data centers that optimize power usage, cut operational costs, and ensure scalable performance for mission-critical workloads.

Shoes That Fit provides new shoes to children in need across the country.

Hardline is an AI voice tool for construction that automatically summarizes phone calls and site walks to write daily logs, extract tasks, and flag urgent items.

Kopacetic AI provides empathic AI-powered communication coaching.

Luxury Presence provides a growth platform for real estate professionals, offering services like real estate websites, SEO, social media management, paid ads management, and an AI CRM.