SoCal.Startups is building the most comprehensive resource for Southern California's tech scene.
SoCal.Startups
Be an early user
San Diego skyline
FROM NAVY BASE TO WIRELESS PIONEER AND BIOTECH HUB

San Diego

401
companies
$25.78B
total raised
B2B, Healthcare, Biotechnology
top industries
Photo: Jon Sullivan · Public domain

The breakdown

401 startups on file in San Diego, spanning B2B, Healthcare, Biotechnology, 366 of 401 have disclosed funding, $25.78B combined, 78 at Series A stage, founding dates span 1985-2026.

A bit of history

The city courted the U.S. Navy in the early 1900s, and Naval Base San Diego opened in 1922, planting the military and engineering roots the region still runs on. UC San Diego professor Irwin Jacobs founded Linkabit in 1968 and later Qualcomm in 1985, inventing wireless technology at the heart of 3G and 4G. A few miles away, fellow UCSD professor Ivor Royston launched Hybritech in 1978, the region's first biotech company. San Diego is now one of the world's top biotech clusters.

Startup & tech events in San Diego

Investors headquartered in San Diego

FusionX VenturesEarly-stage
TVC CapitalGrowth Equity
Qualcomm VenturesSeed through growth (primarily Series A and Series B)
S32Early to growth-stage
selectIon, Inc. hero photo
Series A$5.4M
selectIon, Inc.
San Diego, CA

selectION Therapeutics' si-544 is a first-in-class Kv1.3 blocker and the first disease modifying treatment for T cell autoimmunity. Autoimmunity affects millions worldwide, but current treatments leave the root cause untouched. si-544 is the first therapy to safely and selectively deactivate disease-causing T cells, while preserving immune competence.

Series AHealthcare
Ospitek, Inc. hero photo
Series A$5.4M
Ospitek, Inc.
San Diego, CA · Founded 2018

Ospitek empowers surgical centers with real-time IoT and AI-enhanced solutions, improving workflow efficiency, patient care, and staff coordination. Seamlessly integrate with legacy systems and unlock unparalleled operational visibility with Ospitek’s cutting-edge platform.

Series AHealthcare
$5.3M
Burl Concepts, Inc.
San Diego, CA

BURL Concepts provides innovative ultrasound solutions to instantly access brain performance and guide clinical interventions.

B2B
Seed$5.0M
FUTURCO HEALTH TECHNOLOGIES, INC.
San Diego, CA

Also known as FuturHealth, this San Diego weight-loss company was co-founded and is led by CEO Luke Mahoney.

SeedB2B
Bridgeport Financial Technology, Inc. hero photo
Seed$5.0M
Bridgeport Financial Technology, Inc.
San Diego, CA

Bridgeport Financial Technology, Inc. provides bespoke, digital technology and infrastructure solutions for sophisticated clients across the entire private markets value chain.

SeedFintech
EXCELLOS, Inc hero photo
$5.0M
EXCELLOS, Inc
San Diego, CA · Founded 2020

Excellos Labs is a cell therapy CDMO offering apheresis collection, PBMC and leukopak processing, T/NK cell isolation, and cGMP manufacturing for biotech and pharma.

Healthcare
Series A$4.9M
ECLIPSE BIOINNOVATIONS, INC.
San Diego, CA
Series AHealthcare
WILDCAT DISCOVERY TECHNOLOGIES, INC. hero photo
$4.9M
WILDCAT DISCOVERY TECHNOLOGIES, INC.
San Diego, CA

As leaders in cathode innovation, we develop materials that drive clean energy solutions. Click here to explore our pioneering work in battery technology.

B2B
Series A$4.7M
Transposon Therapeutics, Inc.
San Diego, CA · Founded 2019 · ~11-50 employees

Transposon Therapeutics, Inc. is developing TPN-101 (also known as Censavudine) and other LINE-1 reverse transcriptase inhibitors for the treatment of rare neurodegenerative diseases such as progressive supranuclear palsy (PSP), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD).

Series AHealthcare
XiltriX North America, LLC hero photo
$4.6M
XiltriX North America, LLC
San Diego, CA

XiltriX provides 24/7 live agent monitoring for biotech and biopharma labs and facilities that need to prevent sample loss and maintain compliance.

Healthcare
Resolute Science, Inc. hero photo
Seed$4.5M
Resolute Science, Inc.
San Diego, CA · Founded 2020

Resolute Science, Inc. is a biotechnology company developing a pipeline of first-in-class synthetic drug conjugates, specifically Macrophage-Targeted Conjugates (MAC-TACs), for the treatment of solid tumors.

SeedHealthcare
Seed$4.4M
MemComputing, Inc.
San Diego, CA

Co-founded by physicists Dr. Massimiliano Di Ventra and Dr. Fabio Traversa alongside serial entrepreneur John Beane, previously a founder of ecoATM; investors include DARPA and Revolution's Rise of the Rest Seed Fund.

SeedB2B
Acurion, Inc. hero photo
Seed$4.1M
Acurion, Inc.
San Diego, CA · Founded 2026 · ~201-500 employees

Acurion's OncoGaze™ technology delivers critical genomic insights at the biopsy stage, empowering oncologists to make precision therapy a reality for more patients.

SeedHealthcare
Virchow Medical, Inc. hero photo
Seed$4.1M
Virchow Medical, Inc.
San Diego, CA · Founded 2023

Why Use the Virchow Medical Crow’s Nest Biopsy Catchment System? To Improve Core Needle Biopsy Collection, Tissue Management, and Access to Targeted Diagnostics.

SeedHealthcare
SkySafe, Inc. hero photo
Series B$4.0M
SkySafe, Inc.
San Diego, CA

SkySafe’s advanced drone detection system and airspace intelligence platform enables organizations to identify, track, analyze, and act on unauthorized drone activity.

Series BB2B
$4.0M
MMTM SIX LLC
San Diego, CA · Founded 2023
B2B
$4.0M
SRE Venture 724, LLC
San Diego, CA · Founded 2024
B2B
Series A$3.8M
Thorwear Inc
San Diego, CA · Founded 2019

Also known as Elevate Dynamics; co-founder Daniel Magy previously founded Citadel Defense Company, a counter-drone defense firm that was later acquired by Blue Halo.

Series AB2B
Limber Prosthetics, Inc. hero photo
Seed$3.8M
Limber Prosthetics, Inc.
San Diego, CA · Founded 2022

Precision fit and fully alignable. Unbelievably durable, versatile and affordable. It’s time for the UniLeg.

SeedHealthcare
GetTheReferral.com, Inc. hero photo
$3.8M
GetTheReferral.com, Inc.
San Diego, CA · ~11-50 employees

GTR helps home service companies grow with referral software, branded apps, and automated rewards. Turn happy customers into your best lead source.

B2B
Aervivo, Inc. hero photo
Seed$3.7M
Aervivo, Inc.
San Diego, CA · Founded 2020

Aervivo enables our Partners to provide community wide Gigabit managed WiFi, delighting the communities they serve and generating an outstanding 100%+ IRR, quickly.

SeedB2B
Series B$3.7M
Hotel Santa Clara LLC
San Diego, CA · Founded 2023
Series BB2B
Certis Oncology Solutions, Inc. hero photo
$3.7M
Certis Oncology Solutions, Inc.
San Diego, CA · ~11-50 employees

Certis Oncology Intelligence: predictive AI + advanced cancer models for more insightful data. Translational science, done differently.

Healthcare
Crop Diagnostix, Inc. hero photo
Seed$3.5M
Crop Diagnostix, Inc.
San Diego, CA · Founded 2023

Crop Diagnostix uses plant RNA to detect asymptomatic crop stress before symptoms appear. Asymptomatic Agronomy for partners, retailers, and input providers.

SeedB2B
Series B$3.5M
JumpCode Genomics, Inc.
San Diego, CA

The majority of molecules sequenced are uninformative. Jumpcode Genomics is changing that by helping researchers boost usable NGS data.

Series BHealthcare
Cloud Water Filter, LLC hero photo
$3.3M
Cloud Water Filter, LLC
San Diego, CA · Founded 2020

Meet Cloud RO, an under sink reverse osmosis water system that removes 99% of the toxins in your tap and adds the essential minerals your body needs.

Consumer
Illudent, Inc. hero photo
Seed$3.2M
Illudent, Inc.
San Diego, CA

Illudent (operating as Illudent Therapeutics), a San Diego cancer-treatment biotech, has raised roughly $3.25-5.2M in funding from investors including Ulu Ventures and SeedFolio.

SeedHealthcare
AmbyTech Inc. hero photo
Seed$3.0M
AmbyTech Inc.
San Diego, CA · Founded 2024

AMBYTECH is an IT consulting and digital transformation company based in Paris that assists large enterprises and the banking sector with their digital transformation.

SeedB2B
Series A$3.0M
Ocelot Bio, Inc.
San Diego, CA · Founded 2020

Ocelot Bio closed a $36M Series A led by RA Capital Management, Venrock, and Vivo Capital.

Series AHealthcare
Algenesis Corp hero photo
Seed$3.0M
Algenesis Corp
San Diego, CA

Soleic technology is the world's first fully biodegradable, high performance polyurethane material. Plant-based. Zero microplastics.

SeedB2B
Self Inspection Inc. hero photo
Seed$2.8M
Self Inspection Inc.
San Diego, CA · Founded 2021

Self Inspection uses AI trained on 20M+ images to automate vehicle damage detection, condition reports, and CR scoring — built for dealers, fleets, rentals, and lenders.

SeedB2B
$2.8M
Generative Platforms Inc.
San Diego, CA · Founded 2024
B2B
CARI Health, Inc. hero photo
Seed$2.5M
CARI Health, Inc.
San Diego, CA · Founded 2021

CARI Health empowers clinicians to personalize methadone dosing for every patient.

SeedHealthcare
Seed$2.4M
Hempacco Co., Inc.
San Diego, CA · Founded 2019

Disrupting Tobacco

SeedIndustrials
$2.4M
UCSD Ambulatory Surgery Center, LLC
San Diego, CA
Healthcare
Series A$2.3M
Dracen Pharmaceuticals, Inc.
San Diego, CA

Dracen Pharmaceuticals is a private pharmaceutical company leveraging immuno-metabolism to create new cancer treatments, with their lead candidate, sirpiglenastat (DRP-104), being a unique glutamine inhibitor.

Series AHealthcare
Seed$2.3M
GroGuru, Inc.
San Diego, CA

Founded in 2014 by Patrick Henry, Farooq Anjum, and Jeff Campbell, the agtech soil-sensor company was acquired by Goanna Ag in August 2025.

SeedB2B
Series A$2.2M
Growthsayer, Inc.
San Diego, CA · Founded 2020

Growthsayer was founded by Phillip Geltman, a San Diego-based supply chain specialist who originally built the platform to optimize cannabis industry supply chains before expanding into broader retail demand planning.

Series AB2B
Hauler Hero Inc. hero photo
Seed$2.2M
Hauler Hero Inc.
San Diego, CA · Founded 2021

Hauler Hero is a waste management software solution that helps waste haulers improve their operations, increase efficiency, and reduce costs.

SeedB2B
Biocanic, Inc. hero photo
Seed$2.1M
Biocanic, Inc.
San Diego, CA

Streamline your functional health business with Biocanic to get better better scale and outcomes for you and your clients.

SeedB2B
Angiocrine Bioscience, Inc. hero photo
Series A$2.1M
Angiocrine Bioscience, Inc.
San Diego, CA

Transforming medicine through cellular therapies that restore, regenerate, and repair tissues and organs

Series AHealthcare
$2.0M
RCPS LLC
San Diego, CA · ~1,001-5,000 employees

Roanoke City Public Schools (RCPS) provides educational services and resources for students, families, and the community, including academic programs, special education, and various support departments.

B2B
$1.9M
Exploration Technologies, Inc./DE
San Diego, CA · Founded 2023
B2B
Seed$1.7M
AscentX Medical, Inc.
San Diego, CA

AscentX Medical, Inc. is dedicated to improving quality of life through injectable regenerative therapy focusing on advanced soft tissue engineering using autologous tissue engineering technology with injectable microspheres.

SeedHealthcare
$1.5M
Assumable Technologies Inc.
San Diego, CA · Founded 2024

Operating as Assumable.io, it was co-founded by Ryan Carrillo and Louis Ortiz and drew national coverage (including the New York Times) for its marketplace matching buyers with homes carrying low-rate assumable mortgages.

B2B
Algorithmic Objective Corp. hero photo
$1.5M
Algorithmic Objective Corp.
San Diego, CA · Founded 2019

Objective Corporation creates digital government software solutions in areas like information intelligence, planning & building, and regulatory solutions, aimed at helping government shift to being completely digital and driving stronger communities.

B2B
Series A$1.5M
FOUNDERS FIRST CAPITAL PARTNERS, INC.
San Diego, CA

Founders First Capital Partners - Revenue-Based Funding & Business Advisory

Series AFintech
$1.5M
Limar AI Inc.
San Diego, CA · Founded 2021
B2B
Looq.ai hero photo
Seed$1.5M
Looq.ai
San Diego, CA · Founded 2021

Looq.ai builds an AI handheld photogrammetry platform (qCam/qAI/qApp) for 3D land and utility surveying.

SeedB2B
Seed$1.4M
TPT GLOBAL TECH, INC.
San Diego, CA

TPT Global Tech is a technology holding company with an emphasis on Media Content, Medical Technology and Telecommunications.

SeedB2B
$1.3M
Navega Therapeutics, Inc.
San Diego, CA

Navega Therapeutics is harnessing the precision of zinc-finger and CRISPR based epigenome regulation to enable next-generation gene therapies for chronic pain and precision pain management.

Healthcare
Bench Talent Cloud, Inc. hero photo
Seed$1.3M
Bench Talent Cloud, Inc.
San Diego, CA · Founded 2024

Recruitment CRM for full-time, seasonal, and contract talent. Outreach automation keeps relationships warm and makes rediscovery easy. Works with your ATS.

SeedB2B
$1.2M
Blue Collar Hospitality LLC
San Diego, CA · Founded 2023
Consumer
$1.2M
Califia Pharma, Inc.
San Diego, CA

Discover delicious and nourishing Oatmilks, Almondmilks, Creamers, Coffees, and other natural, non-GMO beverages from Califia Farms. We’re dedicated to powering your wellness transformation by innovating better forms of nourishment with delicious dairy-free plant-based products.

Healthcare
Series A$1.2M
Yatiri Bio, Inc.
San Diego, CA · Founded 2021

Yatiri Bio, Inc. is re-enisioning the pharmaceutical industry's current drug discovery process by integrating patient data sets with testable empirical models to guide patient selection and clinical development, utilizing advanced proteomics and bioinformatics tools and deep learning models.

Series AB2B
Seed$1.1M
Address Insite, Inc.
San Diego, CA · Founded 2023

Address Insite, Inc. provides site acquisition services by simplifying development in the wireless industry and offers wireless consulting services.

SeedB2B
$1.1M
W&CC SPV LLC
San Diego, CA · Founded 2025
B2B
$1.0M
LANDLORD SOLUTIONS SAN DIEGO, PROFESSIONAL Corp
San Diego, CA · Founded 2024
B2B
$1.0M
Delta Trail Crane Services I LLC
San Diego, CA · Founded 2024
B2B
Series A$1.0M
Shreenika Pioneering Inc.
San Diego, CA · Founded 2022

Shreenika Pioneering Inc. creates high-performance, cost-effective chemicals through biotechnology for various industries, aiming to make sustainability an easy economic choice.

Series AB2B