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San Diego

401
companies
$25.78B
total raised
B2B, Healthcare, Biotechnology
top industries
Photo: Jon Sullivan · Public domain

The breakdown

401 startups on file in San Diego, spanning B2B, Healthcare, Biotechnology, 366 of 401 have disclosed funding, $25.78B combined, 78 at Series A stage, founding dates span 1985-2026.

A bit of history

The city courted the U.S. Navy in the early 1900s, and Naval Base San Diego opened in 1922, planting the military and engineering roots the region still runs on. UC San Diego professor Irwin Jacobs founded Linkabit in 1968 and later Qualcomm in 1985, inventing wireless technology at the heart of 3G and 4G. A few miles away, fellow UCSD professor Ivor Royston launched Hybritech in 1978, the region's first biotech company. San Diego is now one of the world's top biotech clusters.

Startup & tech events in San Diego

Investors headquartered in San Diego

FusionX VenturesEarly-stage
TVC CapitalGrowth Equity
Qualcomm VenturesSeed through growth (primarily Series A and Series B)
S32Early to growth-stage
$78.1M
ASCENT HOLDING CO.
San Diego, CA
Fintech
Monarch Quantum, Inc. hero photo
Series A$73.6M
Monarch Quantum, Inc.
San Diego, CA · Founded 2025

We’re an integrated photonics company in California building the light engines that power the next era of quantum technology — from advanced computing to precision sensing.

Series AIndustrials
Series A$72.8M
Kate Therapeutics Inc.
San Diego, CA · Founded 2020

Gene therapy company that emerged from stealth in June 2023 with a $51M Series A co-led by Westlake Village BioPartners, developing AAV-based genetic medicines for muscle and heart disease.

Series AHealthcare
Series A$60.8M
VST BIO Corp
San Diego, CA

VST BIO Corp is a biotechnology company developing first-in-class antibody drugs for the treatment of inflammatory and cardiovascular diseases, including stroke and acute myocardial infarction, as well as sepsis.

Series AHealthcare
Plexium, Inc. hero photo
Series B$60.1M
Plexium, Inc.
San Diego, CA

Plexium is a next-generation targeted protein degradation (TPD) company that discovers Monovalent Direct Degraders and Molecular Glues.

Series BHealthcare
Series B$56.0M
Fabric8Labs, Inc.
San Diego, CA

Electrochemical Additive Manufacturing Mass Production of Next Generation Components High-Resolution Metal 3D Printing at Scale Electrochemical Additive Manufacturing (ECAM) is... Read More

Series BB2B
$50.0M
Strata Millenia, LLC
San Diego, CA · Founded 2023

Strata Millenia is tied to Strata Equity Group, which partnered with Ryan Companies to develop a 278-unit multifamily community within the Millenia master-planned district in Chula Vista.

Real Estate and Construction
Series B$47.4M
SRT Therapeutics, Inc.
San Diego, CA · Founded 2024

SRT Therapeutics was founded in 2024 by former leaders of Prometheus Biosciences, including President & CEO Lauren Otsuki, and launched with roughly $47M in funding.

Series BHealthcare
Series B$42.0M
Evida Biosciences Inc.
San Diego, CA · Founded 2024
Series BHealthcare
Gallant Pet, Inc. hero photo
Series A$35.6M
Gallant Pet, Inc.
San Diego, CA

Gallant offers ready-to-use stem cell therapies that help pets heal from within, restoring vitality and supporting longer, healthier lives.

Series AB2B
Series B$32.9M
Protego Biopharma, Inc.
San Diego, CA

Protego Bio is a clinical-stage biotech developing first-in-class small molecule pharmacological chaperones for AL amyloidosis and other protein misfolding diseases.

Series BHealthcare
Brain Corp hero photo
Series A$32.1M
Brain Corp
San Diego, CA · ~11-50 employees

Brain Corp is an autonomous technology company powering the most proven robots and AI, helping organizations create more productive and intelligent operations.

Series AB2B
Human Longevity, Inc. hero photo
Series B$32.0M
Human Longevity, Inc.
San Diego, CA

The most comprehensive executive health assessment — full-body MRI, whole genome sequencing, 120+ biomarkers & AI analysis in one visit. Starting at $8,000.

Series BHealthcare
Sol-ti, Inc. hero photo
Series B$30.3M
Sol-ti, Inc.
San Diego, CA

Sol-ti sells organic living beverages, including SuperShot, SuperAde, and SuperStix products, which are glass bottled, cold pressed, and made in the USA.

Series BB2B
Turquoise Health Co. hero photo
Series B$30.0M
Turquoise Health Co.
San Diego, CA · Founded 2020

Price with precision. Negotiate with confidence. Turquoise is the platform 300+ healthcare organizations use to make sense of rates, contracts, and compliance.

Series BB2B
Series A$29.1M
SeaSatellites, Inc.
San Diego, CA · Founded 2020

Operates as Seasats; CEO and co-founder Mike Flanigan launched the San Diego autonomous-vessel maker in 2020, and it closed a $20 million Series A backed by Philip Bilden.

Series AB2B
Vektor Medical, Inc. hero photo
Series A$28.9M
Vektor Medical, Inc.
San Diego, CA

Discover vMap - The FDA-Cleared Non-Invasive AI-based Arrhythmia Analysis Solution by Vektor Medical. Improve Cardiac Ablation Efficiencies & Outcomes Today.

Series AHealthcare
Series B$27.0M
Ventyx Biosciences, Inc.
San Diego, CA

The Encinitas-based clinical-stage biotech was acquired by Eli Lilly for $1.2 billion in cash, after IPOing on Nasdaq (VTYX) in 2021.

Series BB2B
Series B$25.2M
858 Therapeutics, Inc.
San Diego, CA

858 Therapeutics (its name references San Diego's 858 area code) has raised $110M across Series A and B rounds led by Versant Ventures and Avidity Partners, with participation from NEA and Insight Partners.

Series BHealthcare
Series A$25.0M
Poseida Therapeutics, Inc.
San Diego, CA

Poseida Therapeutics, a San Diego cell and gene therapy company founded by Eric Ostertag and once listed on Nasdaq as PSTX, was acquired by Roche in a December 2024 tender offer at $9.00/share cash plus a contingent value right.

Series AHealthcare
Arvo Partners, LLC hero photo
$24.9M
Arvo Partners, LLC
San Diego, CA · Founded 2022

Avaamme mahdollisuudet ja takaamme sinulle paremman kasvun: Arvo Partners, täyden palvelun digitaalinen markkinointitoimisto ja tuleva strateginen kumppanisi.

B2B
Foresee Medical, Inc. hero photo
Series C$24.5M
Foresee Medical, Inc.
San Diego, CA

AI-powered risk adjustment software designed to increase the profitability of Medicare risk contracts.

Series CHealthcare
Series B$23.0M
Abrexa Pharmaceuticals, Inc.
San Diego, CA
Series BHealthcare
ClearNote Health, Inc. hero photo
Series D$21.8M
ClearNote Health, Inc.
San Diego, CA

The key to managing cancer is early detection. ClearNote Health makes this possible by finding signals of cancer in the blood early

Series DHealthcare
NanoImaging Services, Inc. hero photo
Seed$19.7M
NanoImaging Services, Inc.
San Diego, CA

NIS, a US based CRO, provides cryo-EM services to accelerate drug discovery, with structural biology, nanoparticle characterization, and GMP compliant imaging.

SeedB2B
Rejuvenate Bio Inc hero photo
Series A$19.5M
Rejuvenate Bio Inc
San Diego, CA

Rejuvenate Bio uses a gene therapy approach to treat chronic, age-related diseases by targeting the root causes of aging to create treatments for chronic conditions affecting both companion animals and humans.

Series AHealthcare
Infracost Inc hero photo
Series A$18.8M
Infracost Inc
San Diego, CA · Founded 2021

FinOps governance for platform teams. Prevent cloud waste and budget overruns before every deploy.

Series AB2B
AristaMD, Inc. hero photo
Series B$17.1M
AristaMD, Inc.
San Diego, CA

AristaMD empowers primary care providers with excellent specialty care - improving patient outcomes with timely, cost-effective access.

Series BHealthcare
Tempo Therapeutics, Inc. hero photo
Series A$16.3M
Tempo Therapeutics, Inc.
San Diego, CA

Tempo Therapeutics is a biotechnology and tissue engineering company based out of San Diego, CA specializing in speeding up patient recovery.

Series AHealthcare
Verve Cloud, Inc. hero photo
Series B$15.8M
Verve Cloud, Inc.
San Diego, CA

An integrated communications platform using cloud-hosted phone, chat, contact center and analytics to meet the challenges of today’s business.

Series BB2B
Series B$15.0M
Primrose Bio, Inc.
San Diego, CA · Founded 2023

Primrose Bio specializes in innovative manufacturing solutions for biotherapeutics and vaccines, setting new standards for quality and production efficiency.

Series BHealthcare
Series A$14.5M
JS-WR JV, INC.
San Diego, CA · Founded 2025

JS-WR JV, Inc. does business as Willie's Remedy+, the CBD/THC beverage and wellness product line created by musician Willie Nelson.

Series AB2B
Series A$14.0M
MiNDERA Corp
San Diego, CA

In only five minutes and a penny-sized patch, Mindera Health technology captures thousands of RNA transcripts. We enable scalable collection and analysis of individualized genetic information to provide actionable, data-driven decisions for patients, providers and payers.

Series AHealthcare
Series A$12.0M
FOUNDERS FIRST CHANGE CATALYST, LLC
San Diego, CA · Founded 2020
Series AFintech
Series A$11.0M
VECKTA
San Diego, CA
Series A
COOLER HEADS CARE, INC. hero photo
Series A$10.6M
COOLER HEADS CARE, INC.
San Diego, CA

Cooler Heads is the creator of Amma™, an FDA-cleared scalp cooling system that helps cancer patients reduce hair loss during chemotherapy. Amma delivers hospital-grade cold-cap therapy that’s simple, portable, and patient-first.

Series AHealthcare
BlueNalu, Inc. hero photo
Series B$10.5M
BlueNalu, Inc.
San Diego, CA

BlueNalu, Inc. develops cell-cultivated seafood, beginning with bluefin tuna toro—crafted with care and produced without fishing.

Series BB2B
Exthymic Corp hero photo
Seed$10.2M
Exthymic Corp
San Diego, CA · Founded 2023

We bring cell therapies to patients through innovative point-of-care manufacturing solutions.

SeedHealthcare
Seed$9.8M
Provisio Medical Technologies Corp
San Diego, CA · Founded 2025

Provisio Medical Technologies Corp. is dedicated to developing innovative solutions for Peripheral Artery Disease, including an automated, integrated smart-catheter technology called the SLT Platform which includes the SLT FLOW, the world's first and only catheter-based volumetric blood flow measurement intra-procedurally.

SeedB2B
Seed$8.8M
HypeVR
San Diego, CA

HypeVR built cinematic volumetric VR capture technology using a 14-camera 6K rig, founded in San Diego in 2015.

SeedB2B
Series A$8.5M
Luxvitae Therapeutics Inc.
San Diego, CA
Series AB2B
Sonocharge Energy, Inc. hero photo
Series A$8.5M
Sonocharge Energy, Inc.
San Diego, CA · Founded 2022

A piezoacoustic platform technology that makes the world’s batteries last longer, charge faster, and be safer.

Series AB2B
EdgeX, Inc. hero photo
Series A$8.5M
EdgeX, Inc.
San Diego, CA · ~11-50 employees

Get instant real-time visibility with EdgeX. Wire-free RTLS, asset tracking, and environmental monitoring. Fast ROI, no IT burden, deployed in hours.

Series AB2B
Series A$7.5M
Alida Biosciences Inc.
San Diego, CA · Founded 2020

EpiPlex™ assay detects RNA modifications by proximity barcoding and short read RNA sequencing, revealing insights into gene regulation for disease research.

Series AHealthcare
Seed$7.5M
Ollie
San Diego, CA
Seed
Auxilium Biotechnologies Inc. hero photo
$7.5M
Auxilium Biotechnologies Inc.
San Diego, CA

We are a pioneering biotechnology company dedicated to producing innovative solutions to treat traumatic nerve injury.

Healthcare
Series B$7.3M
Provisio Medical, Inc.
San Diego, CA
Series BB2B
Vimcal Inc. hero photo
Seed$6.9M
Vimcal Inc.
San Diego, CA

Vimcal is the world’s fastest calendar, beautifully designed for people who have too many meetings. Drag to share availabilities, schedule across time zones, and see all your Outlook and Google calendars in one view.

SeedB2B
Baseline Risk Partners, LLC hero photo
Seed$6.8M
Baseline Risk Partners, LLC
San Diego, CA · Founded 2024

Baseline Risk Partners delivers program administration and underwriting expertise in Specialty Property and Workers’ Compensation.

SeedFintech
$6.8M
Ferret Systems Inc.
San Diego, CA

Search engines and social networks are not designed for due diligence. Ferret’s unparalleled AI platform combined with world class information provides you with exclusive relationship intelligence that can help you avoid high-risk individuals and spot promising opportunities.

B2B
Cellibre, Inc. hero photo
Series A$6.7M
Cellibre, Inc.
San Diego, CA

Cellibre, Inc. uses biology as a manufacturing technology, leveraging nature to create sustainable products through strain engineering, biochemistry, and precision fermentation.

Series AHealthcare
Soutron Holdings LLC hero photo
$6.7M
Soutron Holdings LLC
San Diego, CA · Founded 2025

Technology purpose-built for libraries, archives, and museums for improving Access, Searching, Resource Sharing (interlibrary loan) & Digital Preservation.

B2B
Series A$6.7M
Qureator, Inc.
San Diego, CA

Qureator provides integrated human disease model and AI platform to evaluate treatment efficacy in complex disease models.

Series AHealthcare
Measurabl, Inc. hero photo
$6.5M
Measurabl, Inc.
San Diego, CA · ~201-500 employees

Measurabl offers comprehensive ESG solutions, empowering businesses with data-driven insights for sustainability & compliance. Learn More

B2B
Independa, Inc. hero photo
Series B$6.5M
Independa, Inc.
San Diego, CA · Founded 2024

Independa Health Hub® is a simple to use ecosystem of health & wellness benefits on any screen — TV, tablet, computer, or phone. Many benefits absolutely FREE!

Series BHealthcare
Seed$6.4M
HUME SUPERNATURAL, INC.
San Diego, CA · Founded 2019

Non-toxic deodorants are only good when they're effective. Our plant & mineral based formulas work on all skin types to keep you smelling fresh all day. Aluminum Free Deodorant | Non-Toxic, Paraben & Cruelty Free Free shipping on orders over $25 | Subscribe and save 15%

SeedConsumer
$6.0M
MMTM EIGHT LLC
San Diego, CA · Founded 2024
Real Estate and Construction
Series A$5.7M
CRISPRQC INC.
San Diego, CA · Founded 2021 · ~11-50 employees

Gain unprecedented kinetic insights into your CRISPR workflow with the CRISPR QC’s analytics platform

Series AHealthcare
CARDIFF, INC. hero photo
Series A$5.7M
CARDIFF, INC.
San Diego, CA · Founded 2020

Looking for small business financing? Get approved in 2 minutes or less and get your funds within 24 hours at Cardiff. We have funded over $12 billion for small businesses across the US.

Series AFintech
Serenity EHS Inc. hero photo
Seed$5.5M
Serenity EHS Inc.
San Diego, CA · Founded 2019

Serenity is a unified EHS platform built on ServiceNow for incident management, audits, risk assessments, compliance, and cyber risk — with AI-powered safety insights.

SeedB2B