San Diego
The breakdown
401 startups on file in San Diego, spanning B2B, Healthcare, Biotechnology, 366 of 401 have disclosed funding, $25.78B combined, 78 at Series A stage, founding dates span 1985-2026.
A bit of history
The city courted the U.S. Navy in the early 1900s, and Naval Base San Diego opened in 1922, planting the military and engineering roots the region still runs on. UC San Diego professor Irwin Jacobs founded Linkabit in 1968 and later Qualcomm in 1985, inventing wireless technology at the heart of 3G and 4G. A few miles away, fellow UCSD professor Ivor Royston launched Hybritech in 1978, the region's first biotech company. San Diego is now one of the world's top biotech clusters.
Startup & tech events in San Diego
Investors headquartered in San Diego
OTC Genetic Testing
Series C$152.2MCelladon is a biotechnology company that focuses in the development of molecular therapies to treat heart failure.
Nervana Systems was a San Diego-based company focused on the development of artificial intelligence and deep learning software. The company was acquired by Intel in 2016.
Seed$143.7MCompany
$138.6MCerulean Pharma; Inc is a company founded in 2006 by Ram Sasisekharan.
Series C$37.4MSG Biofuels is a biotechnology company developing renewable fuels.
Series D$62.1MCrown Bioscience is a contract research organisation for drug discovery; best known for oncology models and also working in cardiovascular and metabolic disease; with sites across the United States; E
Series B$59.5MIgnyta is a company that combines medicine and biotechnology for the treatment of cancer and autoimmune diseases.
A company developing therapeutics for veterinary medicine
Series E$65.0MA biopharmaceutical company that develops therapeutics to treat depressive disorders
Series C$50.5MA company focused on the development proteomics
A company that develops therapeutics for the treatment of cancer
$45.3MUpWind Solutions is a San Diego-based company founded in 2007 by Bo Thisted.
Series C$73.2MA life science devices company focused on the discovery and development of protein biomarkers as diagnostic tests
Series D$25.0MZebit is a San Diego-based financial services company offering consumers buy now; pay later on purchases of up to $2;500 interest-free.
$25.0MNirvanix is a San Diego-based company founded in 2007 by Edgard Capdevielle.
Series D$43.3MSotera Wireless is a medical device company engaged in the development of wireless vital signs monitoring devices.
Series F$37.0MAwarepoint is a company founded in 2002 by James Adams.
Series B$34.0MSAVO Group is a San Diego-based company founded in 2010.
$55.0MA company developing reagents for immunology; multicolor flow cytometry and biological system analysis
$71.5MA company developing treatments for Alzheimer’s disease and other neurological diseases
Femta Pharmaceuticals is a biotechnology company that develops protein therapeutics
Series E$20.0MA company developing biologically active compounds and drug candidates
$260.0MA company developing pharmaceutical and diagnostic products to help physicians personalize patient care
Series D$27.2MBridgeWave Communications makes microwave and millimetre wave radios for wireless backhaul; supplying carriers and enterprises with high-capacity point-to-point links.
$20.0MStaccato Communications is a San Diego-based company founded by Roberto Aiello.
Series C$19.6MEventful is a San Diego-based company founded in 2004.
Series D$85.0MDeveloping technologies to produce jet fuel and other biofuels from algae
WildBlue is a San Diego-based web hosting service company founded in 2006.
A biopharmaceutical company developing small molecule therapeutics for respiratory and inflammatory disorders
$69.8MVeoh is a San Diego-based company founded in 2005 by Dmitry Shapiro.
$21.5MSummit Microelectronics designed programmable power management and battery charging integrated circuits for mobile and computing devices; allowing manufacturers to configure charging behaviour in firm
Series D$35.0MBrand of video codec products developed by divx; llc
Series D$28.0MGenoptix is a Carlsbad; California-based medical diagnostics company offering next-generation sequencing for oncology founded in 1999 by Tina Nova.
$92.1MpSemi designs and manufactures RF; power-management and sensor integrated circuits for consumer electronics and communications infrastructure. It is a subsidiary of Japan's Murata Manufacturing.
Tarari is a San Diego-based company founded in 2002.
$15.0MContinuous Computing is a San Diego-based network service company founded in 1998.
$100.0MPacketVideo is a San Diego-based company founded in 1998.
Series C$35.0MSilicon Wave is a San Diego-based semiconductor company.
Series G$1.19BShield AI is a defense-tech company building the world's best AI pilots and next-generation aircraft.
$656.4MDeveloping the next generation of oncology therapies for patients.
$413.0MMirador Therapeutics is focused on discovering and developing precision medicines for immune-mediated inflammatory and fibrotic diseases using its Mirador360™ engine, which harnesses biology, multi-modal data, AI, and advanced analytics.
$400.2MAvidity Biosciences is a company driven by the mission to profoundly improve people's lives by revolutionizing a new class of targeted RNA therapeutics through its Antibody Oligonucleotide Conjugates (AOC™) platform.
$325.4MIambic has created a cutting-edge AI-driven platform to tackle the most challenging design problems in drug discovery and address unmet patient need.
Merck agreed to acquire the San Diego biotech for approximately $9.2 billion in November 2025.
Series C$238.0MBiolinq Inc. develops the Biolinq Shine™ sensor, which is a fully autonomous, needle-free glucose sensor that integrates glucose, activity, and sleep information.
Co-founded by Drew Weissman, the 2023 Nobel Prize winner in Physiology or Medicine for mRNA vaccine research, alongside CAR-T pioneer Carl June; the company was later acquired by AbbVie.
Series F$225.9MRakuten Medical is developing the Alluminox® platform, an investigational platform based on photoimmunotherapy, to transform cancer treatments.
$206.2MFounded by Ken Song and launched with over $370 million (later exceeding $500 million) from investors including Venrock Healthcare Capital Partners, RA Capital Management, and Fairmount.
Series C$200.0MADARx Pharmaceuticals, Inc. is a company that develops RNA medicines leveraging RNA science and proprietary targeted delivery platforms to silence the underlying cause of disease.
Series D$195.7MABA therapy and comprehensive autism care for children, from diagnosis through developmental and medical therapy. Physician-led and in-network. Find a center near you.
Series C$132.6MEndeavor BioMedicines is a clinical-stage biotechnology company developing transformational medicines for life-threatening diseases.
Series B$130.0M
Series C$126.8MA Foresite Labs-incubated biotech backed by Foresite Capital, Qiming Venture Partners, and Samsara BioCapital that raised over $100M before being folded into Candid Therapeutics' $370M launch in 2024.
Series B$100.8MAutobahn aims to improve life health for people affected by CNS disorders by driving the regenerative power of the human body.
TRC 2004 was co-founded by Third Rock Ventures and Two River, the same investor group behind Kite Pharma (sold to Gilead for roughly $11.9B), and later emerged publicly as Candid Therapeutics with a $370M capital raise.
Series A$83.0MFirestorm Labs - Democratize the fight with radically-affordable, mission-adaptable power for air, land, and sea.