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Aerial view looking east toward Santa Ana and Irvine, California
UC IRVINE RESEARCH SPINOUTS AND ORANGE COUNTY'S TECH CORRIDOR

Irvine

231
companies
$8.03B
total raised
B2B, Healthcare, Technology
top industries
Photo: Joe Mabel · CC BY-SA 4.0

The breakdown

231 startups on file in Irvine, spanning B2B, Healthcare, Technology, 215 of 231 have disclosed funding, $8.03B combined, 42 at Series A stage, founding dates span 1985-2026.

A bit of history

UC Irvine opened in 1965 as the intellectual anchor of a master-planned city built by the Irvine Company, and its research park became the seed for what's now called the Tech Coast. Three UCLA graduates started Silicon & Synapse out of a business park near campus in February 1991, working with about $10,000 each; it later became Blizzard Entertainment. Irvine's tech and biotech base has kept growing from there, anchored today by companies like Broadcom.

Investors headquartered in Irvine

Pismo VenturesPre-Seed, Seed, Series A
TCA Venture GroupSeed, Bridge, Early Series A
Sunstone ManagementPre-Seed, Seed
VISEON, INC. hero photo
$2.6M
VISEON, INC.
Irvine, CA

Experience Viseon's Advanced Digital Visualization CRANIALSPINALExperience Viseon's

B2B
$2.5M
SREG LONG BEACH 2 LLC
Irvine, CA · Founded 2025
Real Estate and Construction
Series A$2.3M
Sensible Care Inc.
Irvine, CA · Founded 2022

Sensible Care Inc. offers online therapy and psychiatry for individuals, couples, and families, including adults, teens, and children, with access to in-network care.

Series AHealthcare
OpenWav Inc. hero photo
Seed$2.2M
OpenWav Inc.
Irvine, CA · Founded 2026 · ~11-50 employees

Empowering Indie Artists to Connect, Grow, and Earn - OpenWav

SeedB2B
$2.1M
Zuum Transportation Inc.
Irvine, CA

ZUUM Transportation is a logistics technology company that develops a comprehensive logistics platform including ZUUM Automated Broker for freight brokers to digitize operations and ZUUM BEYOND TMS for shippers.

B2B
$2.0M
Sycamore Honey Partners IV LLC
Irvine, CA · Founded 2026
B2B
BEDROCK SERVICING, INC. hero photo
Series A$2.0M
BEDROCK SERVICING, INC.
Irvine, CA · Founded 2024 · ~11-50 employees

Bedrock Servicing provides a hybrid operating model for private credit lenders. We combine institutional-grade loan servicing with proprietary technology to automate complex asset management, ensure audit-readiness, and eliminate administrative friction.

Series AB2B
$1.9M
TIG ORRIN LLC
Irvine, CA · Founded 2022
Real Estate and Construction
Series A$1.5M
Allevion Therapeutics, Inc.
Irvine, CA

Discover Allevion Therapeutics’ Allevx™ Smart-Band, a wearable device designed to reduce movement-related disorders due to Essential Tremor.

Series AHealthcare
Bookitngo Corp hero photo
Series A$1.4M
Bookitngo Corp
Irvine, CA · Founded 2021 · ~11-50 employees

AI-powered travel technology SaaS platform offering end-to-end solutions for Corporates, B2B, and B2C.

Series AB2B
Seed$1.3M
XOStem Biosciences Ltd.
Irvine, CA · Founded 2018

XOStem Biosciences' listed principals include UC Irvine professor Jonathan Lakey, who co-developed the Edmonton Protocol, the landmark pancreatic islet cell transplantation procedure for treating type 1 diabetes.

SeedB2B
Calico Infrastructure Holdings LLC hero photo
Seed$1.2M
Calico Infrastructure Holdings LLC
Irvine, CA · Founded 2024

Calico Building Services is a leading nationwide provider of commercial janitorial, repair, maintenance and construction services.

SeedIndustrials
Seed$1.1M
Food Safety Systems LLC
Irvine, CA · Founded 2025

Food Safety Systems LLC provides food safety and sanitation resources, compliance, education & training, verification, and technology services primarily for the food services industry in Southern California.

SeedB2B
i3 Specialty, Inc. hero photo
Seed$1.0M
i3 Specialty, Inc.
Irvine, CA · Founded 2026

A unified solution to measure risk, reduce downtime, and strengthen insurance outcomes.

SeedB2B
$1.0M
THUMB TECHNOLGIES, INC.
Irvine, CA · Founded 2020

Thumb Technologies, an Irvine, CA conversational-analytics startup, was co-founded by Jae Chung (previously at Amazon and Autodesk) and Daniel Kopeinigg.

B2B
Pre-Seed$1.0M
Fufu & Tommy LLC
Irvine, CA · Founded 2023
Pre-SeedConsumer
Bluon, Inc. hero photo
$900K
Bluon, Inc.
Irvine, CA

Bluon provides indispensable technical data and support to the HVAC professional industry via our proprietary database and AI platform to increase productivity and provide a clear competitive advantage for our users and partners.

B2B
$755K
FigPIN Collect Awesome Inc.
Irvine, CA

FiGPiNS are hand-crafted enamel character pins featuring a patented backer that serves as a pin clasp AND display stand! FiGPiN elevates collectible pins!

Consumer
Series A$750K
Dap Media, Inc.
Irvine, CA · Founded 2023
Series AB2B
WORLD TREE TECHNOLOGIES INC hero photo
$739K
WORLD TREE TECHNOLOGIES INC
Irvine, CA

World Tree grows Paulownia hardwood through regenerative forestry in partnership with farmers across the Americas.

B2B
YOUATTEST hero photo
Seed$655K
YOUATTEST
Irvine, CA · Founded 2018

YouAttest offers cloud based identity auditing solutions and management We Securely manage user access and ensure compliance with ease Get started today!

SeedB2B
Dardo Studios, Inc. hero photo
Series A$500K
Dardo Studios, Inc.
Irvine, CA · Founded 2023

At Dardo Studios, we provide boutique solutions for comprehensive art creation, including concept art, 3D modeling, animation, VFX, and more. We also offer art direction, recruiting services, and expertise in structuring and managing art departments.

Series AB2B
Bquest, Inc. hero photo
Seed$375K
Bquest, Inc.
Irvine, CA · Founded 2023 · ~11-50 employees

Connect your clients to trusted aging care experts quickly and seamlessly with bQuest. Become their go-to lifeline during family crises through our easy, vetted referral platform.

SeedB2B
TimeCap LLC hero photo
$375K
TimeCap LLC
Irvine, CA · Founded 2020

Timecap is a customizable habit tracker application designed to help users build healthy and productive habits.

B2B
$350K
Uscape Apparel LLC
Irvine, CA

Uscape Apparel LLC creates localized lifestyle apparel for collegiate, destination, and custom markets.

B2B
$320K
Squeeze Software, Inc.
Irvine, CA · Founded 2023

Squeeze Software, Inc. provides forward-thinking IT for businesses.

B2B
$250K
Startup Coach AI Inc
Irvine, CA · Founded 2025
B2B
Seed$87K
ONIT Sciences
Irvine, CA

ONIT Sciences, based in Irvine, brought on Eric Mathur, a globally recognized plant geneticist and molecular biologist, as its Chief Science Officer.

SeedIndustrials
Ecotrak, LLC hero photo
Seed$85K
Ecotrak, LLC
Irvine, CA · Founded 2018

Facility Management Software designed to help businesses save time and money while providing real-time, actionable data.

SeedB2B
Vincit California, Inc. hero photo
$53K
Vincit California, Inc.
Irvine, CA

Vincit is a Nordic digital business partner focusing on commercial solutions, enterprise platforms, and data & AI. We turn digital into business results by combining leading platforms and tailored solutions.

B2B
Essential HR Holdings LLC hero photo
Seed$50K
Essential HR Holdings LLC
Irvine, CA · Founded 2024

Essential HR Services is a team of experienced, professional Human Resources (HR) Consultants specializing in Labor Law Compliance, Employee Relations, HR Administration, Organizational Development, Training, Health and Wellness Programs, and Payroll. Our goal is to deliver quality service, with the utmost integrity.

SeedB2B
Seed$50K
Olobby Inc
Irvine, CA · Founded 2021

Olobby is an all-in-one app for work that provides tasks, files, communication, and more, with both desktop and cloud solutions.

SeedB2B
$35K
FIRSTPEEL INC.
Irvine, CA · Founded 2023

A better dating app, coming soon. Join the waitlist now.

B2B
Scientia Capital Solutions, Inc. hero photo
$20K
Scientia Capital Solutions, Inc.
Irvine, CA · Founded 2025

Scientia Capital Management empowers retail investors with AI-powered investing, wealth management, and investment analysis. Smarter, risk-aware strategies for confident growth.

B2B
Dyverg Brands, LLC hero photo
$20K
Dyverg Brands, LLC
Irvine, CA · Founded 2023

Brands is focused on building our own portfolio—brands that align consumer desire with long-term health and wellness trends.

Industrials
StarCLS, Inc. hero photo
$15K
StarCLS, Inc.
Irvine, CA · Founded 2025

AccessStar empowers independent and meaningful lives for people with intellectual or developmental disabilities by providing various behavioral and developmental services such as group homes, community engagement, and nursing care.

B2B
$468
Phythera Therapeutics Inc.
Irvine, CA · Founded 2021

Phythera Therapeutics, Inc. is a biotechnology company leveraging the power of natural compounds to modulate key biological pathways in cancer and tissue regeneration to improve human health.

Healthcare
Bootstrapped
KanDo
Irvine, CA · 2 employees

KanDo is an AI-powered knowledge and process management tool for creating and managing AI-assisted Standard Operating Procedures, with enterprise-grade multi-tenant authentication and an intelligent knowledge base.

BootstrappedEnterprise Software
Bootstrapped
JouraBooks
Irvine, CA · 1 employees

JouraBooks is desktop-native accounting software for teams migrating off QuickBooks Desktop, offering a practical QBD import path, local-first data control on your own machine, and an AI assistant (Ask Joura) for accounting and back-office work. Currently in private beta.

BootstrappedSoftware as a service (SaaS)
Illuminate Education
Irvine, CA · Founded 2009 · 751 employees
Software as a service (SaaS)
Toshiba America Electronic Components
Irvine, CA · Founded 1989 · 267 employees

Toshiba America Electronic Components is the North American electronic components arm of Toshiba; established in 1989.

Semiconductor
Ambros Therapeutics
Irvine, CA

Ambros Therapeutics is a clinical-stage biotechnology company focused on developing innovative and transformative medicines for diseases with a high unmet medical need, with its lead investigational program targeting complex regional pain syndrome type 1 (CRPS-1).

Healthcare
Anchr
Irvine, CA

Anchr provides AI agents for physical operations in industries such as food distribution, industrial and MRO, healthcare and pharma, building and technical supplies, and consumer packaged goods.

B2B
Synergetics.AI
Irvine, CA

Synergetics.AI offers a trusted agentic infrastructure platform that allows AI agents to identify, communicate, and transact securely across enterprise boundaries.

B2B
Boumarang Inc. hero photo
Boumarang Inc.
Irvine, CA · Founded 2024

Boumarang builds hydrogen-powered, AI-enabled unmanned systems for air and maritime operations. Long endurance. Domestic IP. Dual-use by design.

B2B
FFR GROUP LLC
Irvine, CA
Fintech
Azurite Software Holdings, Inc.
Irvine, CA · Founded 2023
B2B
Eagle Mountain Data Inc hero photo
Eagle Mountain Data Inc
Irvine, CA · Founded 2025 · ~11-50 employees

Eagle Mountain Data provides next-generation infrastructure, including GPU services, storage, and networking, designed for complex AI workloads and real-time responsiveness at the edge.

B2B
Entelexo Biotherapeutics
Irvine, CA · Founded 2021 · 3 employees

Creating a New Class of Drugs to Address Incurable Autoimmune Diseases

Y CombinatorHealthcare
Korso
Irvine, CA · Founded 2026 · 3 employees

The AI-native agency

Y CombinatorB2B
Vena Vitals
Irvine, CA · Founded 2020 · 9 employees

A small sticker that monitors blood pressure continuously

Y CombinatorHealthcare