Healthcare
Healthcare startups in Irvine. Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Series C$100.4MJenaValve's investors include Bain Capital Life Sciences and the Qatar Investment Authority.
Series E$99.5MNo math. No dosing decisions. Just freedom to live.
Series E$50.0MEledon Pharmaceuticals was co-founded and is led by CEO David-Alexandre Gros, a physician and serial biotech entrepreneur, with investors including BVF Partners, RA Capital Management, and Blue Owl Capital.
Oncocyte is a publicly traded diagnostics company (Nasdaq: OCX) that later renamed itself Insight Molecular Diagnostics and relocated its headquarters to Nashville.
$42.0MRestora Medical was founded by Dr. Quan Ni, who previously co-founded Inspire Medical Systems (Nasdaq: INSP).
Series B$27.5M
Seed$7.9MCelestial Therapeutics is developing novel therapies based on innovative and groundbreaking science to treat, prevent and cure infectious diseases, rare diseases and cancers.
Seed$7.2MThe Tally Surgical retained sponge prevention solution utilizes UHF RFID to simplify and speed an accurate count of surgical sponges and towels.
$4.5MNorwegian medical device company Photocure ASA announced in 2026 it is acquiring Vesica Health, whose bladder-cancer diagnostic AssureMDx has received FDA Breakthrough Device Designation.
Seed$4.4MFounded in 2007 by cardiothoracic surgeon Dr. Edward Boyle and Paul Molloy to develop anti-occlusion surgical drainage devices; the Anaheim-based company's PleuraFlow system was later distributed exclusively in the US by Maquet Medical Systems.
Series A$4.2MTenovi remote patient monitoring 40+ FDA-cleared hardware devices power RPM and RTM programs with the first plug-and-play Cellular Gateway.
Series A$3.3MLaguna Tech USA is an Irvine-based transcatheter heart valve company led by CEO Gilbert Madrid; it has raised over $8M, including investment from MedTech Innovator.
Series A$2.3MCo-founded in 2017 by Paul Kim, an Army veteran, the teletherapy company raised a $13M Series A led by Volition Capital.
Series A$1.5MDiscover Allevion Therapeutics’ Allevx™ Smart-Band, a wearable device designed to reduce movement-related disorders due to Essential Tremor.
Seed$468Phythera Therapeutics, Inc. is a biotechnology company leveraging the power of natural compounds to modulate key biological pathways in cancer and tissue regeneration to improve human health.
A small sticker that monitors blood pressure continuously
Creating a New Class of Drugs to Address Incurable Autoimmune Diseases