Healthcare
22 healthcare startups based in Irvine, $540.0M raised total, led by Modulated Imaging, Inc. ($9.9M raised). See what Healthcare means more broadly on the Healthcare industry page.
The breakdown
19 of 22 companies have disclosed funding, $540.0M combined, 5 at Series A stage, making up 10% of the 231 Irvine startups on file across every industry, founding dates span 2005-2023.
Companies
Modulated Imaging; Inc. is an Irvine; California-based company founded in 2005.
Axonics Modulation Technologies is a sacral Neuromodulation Device founded in 2013.
Levyx provies an enterprise-class data management platform for a variety of big data applications.
Alphaeon is an Irvine; California-based healthcare company founded in 2013.
PrescribeWellness is an Irvine; California-based company founded in 2010 by Al Babbington.
JenaValve Technology Inc. offers the Trilogy Transcatheter Heart Valve, which is an FDA-approved TAVR system specifically designed for aortic regurgitation, utilizing locator technology for alignment and secure anchoring.
Oncocyte is a publicly traded diagnostics company (Nasdaq: OCX) that later renamed itself Insight Molecular Diagnostics and relocated its headquarters to Nashville.
Restora Medical, Inc. focuses on Restorative Sleep Apnea Therapy using Targeted Nerve Stimulation.

SmartHealth Holdings, Inc. drives transformative innovation in healthcare diagnostics, including groundbreaking imaging systems for pathology, advanced vascular diagnostics, and oncology-focused solutions, notably with its pioneering MUSE technology for slide-free digital pathology.

Celestial Therapeutics is developing novel therapies based on innovative and groundbreaking science to treat, prevent and cure infectious diseases, rare diseases and cancers.

The Tally Surgical retained sponge prevention solution utilizes UHF RFID to simplify and speed an accurate count of surgical sponges and towels.

Vesica Health, Inc. brings clarity to clinical decisions by combining next-generation molecular diagnostics and Blue Light Cystoscopy to improve early detection and diagnosis for bladder cancer patients, and offers the noninvasive urine-based AssureMDx test to identify hematuria patients at increased risk for bladder cancer.
ClearFlow develops medical technologies including PleuraFlow Active Clearance Technology to reduce Retained Blood Syndrome complications and ClearFix Rigid Sternal Fixation for stabilization and fixation of anterior chest wall fractures.

Tenovi remote patient monitoring 40+ FDA-cleared hardware devices power RPM and RTM programs with the first plug-and-play Cellular Gateway.

Laguna Tech USA is developing the ZETA Transcatheter Aortic Valve System, a balloon-expandable valve solution designed for Aortic Regurgitation and Aortic Stenosis.
Sensible Care Inc. offers online therapy and psychiatry for individuals, couples, and families, including adults, teens, and children, with access to in-network care.
Discover Allevion Therapeutics’ Allevx™ Smart-Band, a wearable device designed to reduce movement-related disorders due to Essential Tremor.
Phythera Therapeutics, Inc. is a biotechnology company leveraging the power of natural compounds to modulate key biological pathways in cancer and tissue regeneration to improve human health.
Ambros Therapeutics is a clinical-stage biotechnology company focused on developing innovative and transformative medicines for diseases with a high unmet medical need, with its lead investigational program targeting complex regional pain syndrome type 1 (CRPS-1).

Creating a New Class of Drugs to Address Incurable Autoimmune Diseases

A small sticker that monitors blood pressure continuously