SoCal.Startups is building the most comprehensive resource for Southern California's tech scene.
SoCal.Startups
Be an early user
IRVINE

Healthcare

22 healthcare startups based in Irvine, $540.0M raised total, led by Modulated Imaging, Inc. ($9.9M raised). See what Healthcare means more broadly on the Healthcare industry page.

22
companies
$540.0M
total raised

The breakdown

19 of 22 companies have disclosed funding, $540.0M combined, 5 at Series A stage, making up 10% of the 231 Irvine startups on file across every industry, founding dates span 2005-2023.

Companies

Series B$9.9M
Modulated Imaging, Inc.
Irvine, CA · Founded 2005

Modulated Imaging; Inc. is an Irvine; California-based company founded in 2005.

Series BHealthcare
Series C$67.6M
Axonics Modulation Technologies
Irvine, CA · Founded 2013 · 751 employees

Axonics Modulation Technologies is a sacral Neuromodulation Device founded in 2013.

Series CHealthcare
Series A$5.4M
Levyx, Inc.
Irvine, CA · Founded 2013 · 31 employees

Levyx provies an enterprise-class data management platform for a variety of big data applications.

Series AHealthcare
Series B$80.1M
Alphaeon
Irvine, CA · Founded 2013 · 126 employees

Alphaeon is an Irvine; California-based healthcare company founded in 2013.

Series BHealthcare
$1.0M
PrescribeWellness
Irvine, CA · Founded 2010 · 126 employees

PrescribeWellness is an Irvine; California-based company founded in 2010 by Al Babbington.

Healthcare
$123.1M
Bright Uro, Inc.
Irvine, CA · Founded 2021
Healthcare
Series C$100.4M
JenaValve Technology Inc
Irvine, CA

JenaValve Technology Inc. offers the Trilogy Transcatheter Heart Valve, which is an FDA-approved TAVR system specifically designed for aortic regurgitation, utilizing locator technology for alignment and secure anchoring.

Series CHealthcare
$47.8M
Oncocyte Corp
Irvine, CA

Oncocyte is a publicly traded diagnostics company (Nasdaq: OCX) that later renamed itself Insight Molecular Diagnostics and relocated its headquarters to Nashville.

Healthcare
$42.0M
Restora Medical, Inc.
Irvine, CA · Founded 2023

Restora Medical, Inc. focuses on Restorative Sleep Apnea Therapy using Targeted Nerve Stimulation.

Healthcare
Smart Health Diagnostics Co hero photo
Series B$27.5M
Smart Health Diagnostics Co
Irvine, CA

SmartHealth Holdings, Inc. drives transformative innovation in healthcare diagnostics, including groundbreaking imaging systems for pathology, advanced vascular diagnostics, and oncology-focused solutions, notably with its pioneering MUSE technology for slide-free digital pathology.

Series BHealthcare
CELESTIAL THERAPEUTICS INC. hero photo
Seed$7.9M
CELESTIAL THERAPEUTICS INC.
Irvine, CA · Founded 2019

Celestial Therapeutics is developing novel therapies based on innovative and groundbreaking science to treat, prevent and cure infectious diseases, rare diseases and cancers.

SeedHealthcare
Tally Surgical, Inc. hero photo
Seed$7.2M
Tally Surgical, Inc.
Irvine, CA · Founded 2020

The Tally Surgical retained sponge prevention solution utilizes UHF RFID to simplify and speed an accurate count of surgical sponges and towels.

SeedHealthcare
Vesica Health, Inc. hero photo
$4.5M
Vesica Health, Inc.
Irvine, CA · Founded 2022

Vesica Health, Inc. brings clarity to clinical decisions by combining next-generation molecular diagnostics and Blue Light Cystoscopy to improve early detection and diagnosis for bladder cancer patients, and offers the noninvasive urine-based AssureMDx test to identify hematuria patients at increased risk for bladder cancer.

Healthcare
Seed$4.4M
CLEARFLOW, Inc
Irvine, CA · ~11-50 employees

ClearFlow develops medical technologies including PleuraFlow Active Clearance Technology to reduce Retained Blood Syndrome complications and ClearFix Rigid Sternal Fixation for stabilization and fixation of anterior chest wall fractures.

SeedHealthcare
Tenovi Co. hero photo
Series A$4.2M
Tenovi Co.
Irvine, CA · Founded 2021

Tenovi remote patient monitoring 40+ FDA-cleared hardware devices power RPM and RTM programs with the first plug-and-play Cellular Gateway.

Series AHealthcare
Laguna Tech USA, Inc. hero photo
Series A$3.3M
Laguna Tech USA, Inc.
Irvine, CA · Founded 2022

Laguna Tech USA is developing the ZETA Transcatheter Aortic Valve System, a balloon-expandable valve solution designed for Aortic Regurgitation and Aortic Stenosis.

Series AHealthcare
Series A$2.3M
Sensible Care Inc.
Irvine, CA · Founded 2022

Sensible Care Inc. offers online therapy and psychiatry for individuals, couples, and families, including adults, teens, and children, with access to in-network care.

Series AHealthcare
Series A$1.5M
Allevion Therapeutics, Inc.
Irvine, CA

Discover Allevion Therapeutics’ Allevx™ Smart-Band, a wearable device designed to reduce movement-related disorders due to Essential Tremor.

Series AHealthcare
$468
Phythera Therapeutics Inc.
Irvine, CA · Founded 2021

Phythera Therapeutics, Inc. is a biotechnology company leveraging the power of natural compounds to modulate key biological pathways in cancer and tissue regeneration to improve human health.

Healthcare
Ambros Therapeutics
Irvine, CA

Ambros Therapeutics is a clinical-stage biotechnology company focused on developing innovative and transformative medicines for diseases with a high unmet medical need, with its lead investigational program targeting complex regional pain syndrome type 1 (CRPS-1).

Healthcare
Entelexo Biotherapeutics
Irvine, CA · Founded 2021 · 3 employees

Creating a New Class of Drugs to Address Incurable Autoimmune Diseases

Y CombinatorHealthcare
Vena Vitals
Irvine, CA · Founded 2020 · 9 employees

A small sticker that monitors blood pressure continuously

Y CombinatorHealthcare