Medical Technology startups in Southern California
A deep biotech research base and a growing bench of medical device and diagnostics startups.
Companies

Intrigue Health aims to empower patients and healthcare providers with home diagnostics.

For three generations, our family has pioneered the protection and restoration of our ocean. That’s why we founded SeaVoir – to create high quality ocean-derived products that support human health and ocean restoration.

Brands is focused on building our own portfolio—brands that align consumer desire with long-term health and wellness trends.
MAPLE FUNG MD INC provides biotech consulting services, including fractional CMO roles and protocol design, and also offers per diem nephrology care and serves as a clinical trial investigator.
Phythera Therapeutics, Inc. is a biotechnology company leveraging the power of natural compounds to modulate key biological pathways in cancer and tissue regeneration to improve human health.
Founded by Dr. Susanne B. Nicholas, a UCLA nephrology professor, to commercialize kidney-disease research from her own lab.

Scheduling and workforce management SaaS for home healthcare providers
NeuroSigma is a bioelectronic medical device company that uses non-invasive trigeminal-nerve stimulation to treat chronic neurological disorders, including an FDA-cleared device for pediatric ADHD.

Condor is an AI-powered platform that unifies clinical, operational, and financial data into a single source of truth for life sciences companies to manage R&D finances.

MedicalMex helps and protects international patients traveling to Mexico for affordable medical services, including weight loss surgery, plastic surgery, pain management, hair restoration, dental, vascular, more procedures, orthopedic surgery, and general surgery.

Novoron Bioscience is pioneering lipoprotein-receptor drug development to repair damage and degeneration of the brain, spinal cord, and beyond, with therapies to block the spread of prion-like proteins and enhance spinal cord regeneration.

Kenai Therapeutics is a clinical-stage biotechnology company advancing off-the-shelf dopamine neuron replacement cell therapies and gene-modified medicines to cure neurological conditions.

Bienestar Human Services provides full-service medical care, HIV/AIDS treatment and prevention, sexual health, mental health, substance use counseling, and medication-assisted treatment, alongside community services like men's health, trans health, harm reduction, youth empowerment, emergency housing, and food bank services.

St. John’s Community Health is dedicated to providing compassionate, high-quality healthcare for all, offering medical, dental, pediatric, women's health, mental health, substance use, and homeless health services, as well as patient programs like case management and health education.

Midi Health is a virtual healthcare clinic for women that provides personalized care plans including treatments, products, and guidance designed around individual hormones and symptoms.
Ember LifeSciences applies proprietary heating and cooling technology to the healthcare industry, offering self-refrigerated, cloud-based shipping boxes called Ember Cubes.
Ambros Therapeutics is a clinical-stage biotechnology company focused on developing innovative and transformative medicines for diseases with a high unmet medical need, with its lead investigational program targeting complex regional pain syndrome type 1 (CRPS-1).

Neomorph develops molecular glue degraders to target and destroy disease-causing proteins by engineering neomorphic protein surfaces.

Sidewinder Therapeutics pioneers the next generation of bispecific antibody-drug conjugates (ADCs) to expand the therapeutic window for patients with difficult-to-treat cancers.

RyboDyn is pioneering immunotherapy development by unlocking the dark proteome with its proprietary RyboCypher™ technology to reveal hidden targets and transform biological signals into breakthrough therapies.
Replicate Bioscience leverages self-replicating RNA (srRNA) vectors to advance treatments across therapeutic areas like infectious disease, oncology, and autoimmune disorders.

Recludix Pharma is developing new oral precision medicines with selective inhibitors to tackle protein targets for people living with inflammatory diseases.

Oralucent sells a light therapy sonic toothbrush and related accessories like O2 gel teeth whitener and replacement brush heads for oral health.

Creating a New Class of Drugs to Address Incurable Autoimmune Diseases

OrangeTwist is a med spa that provides treatments ranging from facials to full-body transformations and also offers medical weight loss treatments.


Healthcare Price Transparency APIs and Data Products

Citadel EHS is an environmental, health, safety, and sustainability (EHS&S) consulting firm that helps organizations manage EHS&S challenges across industries and creates safer, more sustainable spaces.
Angitia Biopharmaceuticals is a clinical-stage biotechnology company focused on the discovery and development of innovative therapeutics for serious musculoskeletal diseases.

Macro Biologics designs, patents, and produces advanced biomaterials for healthcare, food and water applications, and packaging.

A small sticker that monitors blood pressure continuously

Oral drugs to halt neurodegeneration

We are using the gut microbiome to end cancer.


Fermentation-derived natural products to solve health problems


Bioengineered kidneys for patients with kidney failure


Clinical skincare tested on diverse skin, now available in Sephora.

High quality mRNA for therapeutic application


Reinventing respiration monitoring
.png&w=3840&q=75)

ML to predict and prevent pregnancy complications

B2B supplier of fresh/healthy packaged food

MedCrypt gives medical device vendors cybersecurity features in a few…

Float is the full-stack platform for Specialty Pharma


A new way of seeing inside the human body.


The API for Diagnostic Test Analysis (COVID-19, FLU, RSV, STD,…

Colorescience offers mineral sunscreens and clinical skincare products.
Anchr provides AI agents for physical operations in industries such as food distribution, industrial and MRO, healthcare and pharma, building and technical supplies, and consumer packaged goods.
Primmune Therapeutics is a clinical-stage biotechnology company focused on developing systemic cancer immunotherapies that activate the immune system in a precise and controlled manner.
Sarmal is developing proprietary single molecule DNA sequencing technology and target detection technology for genomic detection.
Subsense is building the first NanoBCI, a non-surgical, nanoparticle-based Brain-Computer Interface platform designed to transform the treatment of neurological disorders by uniting the human brain, technology, and AI.


Responsive materials, better lives.


Government-funded online addiction treatment


CRISPR powered Diagnostics with results in minutes.

Sharpen DTX, by Resiliency Technologies, Inc., provides mental health literacy tools and prevention toolkits for schools, families, colleges, and community organizations to improve mental wellness and resiliency.
Keyframe Labs builds human foundation models that power lifelike, interactive avatars with photorealism, emotion, and real-time latency.

Roadrunner AI provides a workspace for the search, analysis, and synthesis of scientific literature, purpose-built for the rigor and methods of life sciences, healthcare, and biomedical research.

Our mobile app reduces chronic pain for 100 million Americans.