Medical Technology startups in Southern California

Acurion's OncoGaze™ technology delivers critical genomic insights at the biopsy stage, empowering oncologists to make precision therapy a reality for more patients.

Why Use the Virchow Medical Crow’s Nest Biopsy Catchment System? To Improve Core Needle Biopsy Collection, Tissue Management, and Access to Targeted Diagnostics.

PiLogic is a dual-use company that revolutionizes aerospace by delivering precise, efficient, and mathematically grounded AI solutions for critical dual-use aerospace applications like tracking, diagnosis, and sensor fusion.

Meduloc provides minimally invasive, intramedullary implants that offer stable fixation and secure reduction for all types of small, long-bone fractures.

Children’s healthcare products designed to make sick days more playful. Playhouse MD empowers kids to feel confident and connected — because a dose of play goes a long way.

ChromaCode is a leading provider of HDPCR™ multiplexing technology for genomic solutions. Our breakthrough platform enables labs, physicians, and patients to access actionable biomarkers faster and more affordably. With HDPCR™, you can get critical and complete data, analyzed with simplicity, without paying for excess information.

2A Biosciences is pioneering neural restoration by advancing precision agonists to restore neural circuitry and immune balance, having demonstrated in vivo nerve regeneration via 5-HT2A modulation.

Precision fit and fully alignable. Unbelievably durable, versatile and affordable. It’s time for the UniLeg.

Co-founded by Jeffrey Port and William Blair; the company was acquired by Merit Medical Systems, expanding Merit's therapeutic oncology portfolio.

Virgo builds frontier AI models to solve diseases mediated by the gut. Our flagship model, EndoDINO, was trained on the largest GI endoscopy dataset.

Certis Oncology Intelligence: predictive AI + advanced cancer models for more insightful data. Translational science, done differently.

ProCode Inc. provides an AI-Powered Medical Billing & Coding Copilot.

Kindra is transforming vaginal health and sexual wellness for women navigating their changing bodies and profound hormonal shifts.

Crop Diagnostix uses plant RNA to detect asymptomatic crop stress before symptoms appear. Asymptomatic Agronomy for partners, retailers, and input providers.

Make medication work as intended. Custom Health connects pharmacy, in-home technology, and pharmacist-led care for 98% adherence and improved outcomes.

The majority of molecules sequenced are uninformative. Jumpcode Genomics is changing that by helping researchers boost usable NGS data.

Does business as Mahmee, a maternal health startup co-founded by Melissa Hanna that raised $3M in seed funding from Mark Cuban and Serena Williams.

Laguna Tech USA is developing the ZETA Transcatheter Aortic Valve System, a balloon-expandable valve solution designed for Aortic Regurgitation and Aortic Stenosis.

Illudent (operating as Illudent Therapeutics), a San Diego cancer-treatment biotech, has raised roughly $3.25-5.2M in funding from investors including Ulu Ventures and SeedFolio.

VivaMed BioPharma is a clinical-stage biopharma advancing new chemical entities and repurposed drugs across neurology, pain, psychiatry, pulmonology, and rheumatology. Operator-led development, global partnerships.

Effortless, science-backed oral microbiome insights from saliva. Decode your saliva for personalized wellness.

Ocelot Bio closed a $36M Series A led by RA Capital Management, Venrock, and Vivo Capital.

Strengthen care and improve patient outcomes by prescribing a healthier lifestyle

Amydis is the leader in developing a new class of diagnostic compounds that enable digital detection and monitoring of human disease-related molecular biomarkers through standard ocular imaging cameras.

Facile is a clinically-kind skincare brand and aesthetics boutique featuring Core Four products and targeted Super Skin serums. Dermatologist-formulated, easy to follow and designed with your best skin in mind. Good skin should be easy.

Through its health & fitness AI platform, PEAR creates personalized digital coaching experiences to help people move smarter, get healthier, and live happier.

MedVector connects healthcare providers with clinical trials by protecting the patient/doctor relationship, compensating for additional workload, aiding in patient identification, and enhancing patient care through advanced medicine.

Biologic solutions to optimize enthesis reformation, EnFix® is the future of bone to tendon healing.

Discover OrthoRPM, transforming home exercise programs with guided rehabilitation, motion tracking, and connected digital therapy solutions for clinics without paper.

CARI Health empowers clinicians to personalize methadone dosing for every patient.

SureCount SmartTrays streamline surgical instrument management, reducing errors, speeding counts, and improving safety across OR and SPD teams.

TruBrain is a nootropic created by UCLA-trained neuroscientists founded in 2012.

Sensible Care Inc. offers online therapy and psychiatry for individuals, couples, and families, including adults, teens, and children, with access to in-network care.

Formerly operated Gamma Knife stereotactic radiosurgery centers; the publicly traded company (OTC: USNU) renamed itself Elite Health Systems Inc. in September 2024.

Dracen Pharmaceuticals is a private pharmaceutical company leveraging immuno-metabolism to create new cancer treatments, with their lead candidate, sirpiglenastat (DRP-104), being a unique glutamine inhibitor.

Options MD was a telehealth company for treatment-resistant depression, connecting patients with providers for options like ketamine-assisted therapy and TMS.

Varsity Healthcare Partners builds leading healthcare companies, employing a differentiated partnership model.

Streamline your functional health business with Biocanic to get better better scale and outcomes for you and your clients.

Transforming medicine through cellular therapies that restore, regenerate, and repair tissues and organs

A28 Therapeutics is a clinical stage biopharmaceutical company developing a novel platform technology to treat multiple cancer types

Synedgen develops first-in-class therapeutics that improve patient outcomes by promoting barrier function to repair mucosal injury, with their lead asset MIIST305 aimed at repairing GI mucosal injury.

AscentX Medical, Inc. is dedicated to improving quality of life through injectable regenerative therapy focusing on advanced soft tissue engineering using autologous tissue engineering technology with injectable microspheres.

Review medical records in minutes, not days. Our AI-powered software creates instant summaries and chronologies so you can focus on what matters.

CancerVax is a pre-clinical biotech company developing a novel Universal Cancer Treatment Platform that uses artificial intelligence to disguise cancer cells to look like measles, thereby tricking the body's immune system into killing them.

Discover Allevion Therapeutics’ Allevx™ Smart-Band, a wearable device designed to reduce movement-related disorders due to Essential Tremor.

TPT Global Tech is a technology holding company with an emphasis on Media Content, Medical Technology and Telecommunications.

Navega Therapeutics is harnessing the precision of zinc-finger and CRISPR based epigenome regulation to enable next-generation gene therapies for chronic pain and precision pain management.

Discover delicious and nourishing Oatmilks, Almondmilks, Creamers, Coffees, and other natural, non-GMO beverages from Califia Farms. We’re dedicated to powering your wellness transformation by innovating better forms of nourishment with delicious dairy-free plant-based products.

Paralos Bioscience Inc. is developing phage-drug conjugates using a modular M13 phage drug delivery platform designed to concentrate payloads at specific targets.