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Medical Technology startups in Southern California

A deep biotech research base and a growing bench of medical device and diagnostics startups.

477
companies
$20.52B
total raised
43
cities

Companies

Series D$328.8M
ViaCyte
San Diego, CA · Founded 1999 · 126 employees

ViaCyte is a biotechnology company using stem cells to create pancreatic beta cell precursors for treating diabetes.

Series DStem cell
Series C$258.0M
RayzeBio
San Diego, CA · 51 employees

Operator of a biotechnology company intended to improve outcomes for people with cancer. The company offers a pipeline against validated oncology targets to deliver radioisotopes that emit alpha parti

Series CBiomedical engineering
Series B$40.0M
Phanes Therapeutics
San Diego, CA

Phanes Therapeutics is a treatments for solid tumors and eye diseases.

Series BBiomedical engineering
Series A$40.0M
Seed Health
Los Angeles, CA · Founded 2015 · 254 employees

Seed Health is a microbial sciences company selling probiotics developed around clinical research rather than marketing claims. Its Daily Synbiotic pairs specific probiotic strains with a prebiotic in

Series AProbiotics
Series D$799.0M
Biosplice Therapeutics
San Diego, CA · Founded 2008 · 30 employees

Biosplice Therapeutics is a clinical-stage biotechnology company developing lorecivivint; an injectable small-molecule CLK/DYRK-family inhibitor for knee osteoarthritis.

Series DBiotechnology
$4.7M
Stax Health, Inc.
Santa Monica, CA

Stax Health; Inc. is a Santa Monica; California-based company.

Healthtech
Series A$58.0M
Fortis Therapeutics
San Diego, CA · Founded 2016 · 31 employees

Fortis Therapeutics is a San Diego; CA-based immuno-oncology biotech company

Series ABiomedical engineering
Series D$114.0M
Neurelis Inc
San Diego, CA · Founded 2007 · 126 employees

Neurelis Inc. is a private specialty pharmaceutical company based in San Diego; California; US; providing treatment options for epilepsy and central nervous system disorders.

Series DBiotechnology
Series B$267.0M
Vividion Therapeutics
San Diego, CA · Founded 2017 · 126 employees

Vividion Therapeutics is a proprietary Screening founded in 2017.

Series BEngineering
Series B$34.1M
Iridia
San Diego, CA · Founded 2016 · 31 employees

Iridia is a DNA researching and developing company.

Series BBiotechnology
Series C$132.1M
Truvian Sciences
San Diego, CA · Founded 2015

Truvian Sciences is a San Diego-based company developing automated; benchtop diagnostic systems founded in 2015.

Series CEngineering
Series C$80.0M
Pipeline Therapeutics
San Diego, CA · Founded 2017 · 31 employees

Pipeline Therapeutics is a small Molecule for MS founded in 2017.

Series CBiopharmaceutical
Series D$141.8M
Genalyte
San Diego, CA · Founded 2019 · 126 employees

Genalyte is an American medical analytics and diagnostics company.

Series DTechnology
Series A$77.0M
IconOVir Bio
San Diego, CA · 31 employees

IconOVir Bio is an oncolytic Virus Therapy.

Series ABiotechnology
Series B$21.9M
ConsejoSano
Los Angeles, CA · Founded 2017 · 126 employees

A health care company in California that focuses on improving quality of care.

Series BHealthcare
Series B$155.6M
Locanabio
San Diego, CA · Founded 2016 · 31 employees

Locanabio is a San Diego; California-based biotechnology company developing RNA-targeting gene therapies.

Series BGenealogy
Series C$45.0M
Well Health Inc.
Santa Barbara, CA · Founded 2015 · 351 employees

Well Health Inc. is a Santa Barbara; California-based healthcare company founded in 2015.

Series CHealthcare
Series D$255.0M
Ambrx
San Diego, CA · Founded 2003 · 126 employees

A biopharmaceutical company developing protein therapeutics

Series DBiomedical engineering
Series D$95.0M
TigerConnect
Santa Monica, CA · Founded 2010 · 274 employees

Developer of a healthcare communications platform intended to connect doctors; nurses; care teams and patients on a common interface.

Series DCybersecurity
Series E$171.5M
Novus Therapeutics
Irvine, CA · Founded 2017 · 31 employees

Novus Therapeutics is an Irvine; California-based company founded in 2017.

Series ETechnology
Series A$29.0M
Libra Therapeutics
San Diego, CA · Founded 2019 · 6 employees

Libra Therapeutics is a small Molecules for Neurodegenerative Indications founded in 2019.

Series AEngineering
$75.0M
PatientPop
Santa Monica, CA · Founded 2014 · 751 employees

PatientPop is a Santa Monica; California-based healthcare software products company offering front office automation including appointment scheduling founded by Travis Schneider.

Technology
Series C$27.0M
mPulse Mobile
Los Angeles, CA · Founded 2014 · 215 employees

A mobile health engagement service in California that focuses on improvement in health outcomes and business efficiencies.

Series CTechnology
Series C$107.0M
Kernel
Santa Monica, CA · Founded 2016 · 6 employees

Kernel is a neuroscience and engineering company founded in 2016; based in Los Angeles. Kernel is developing neuroprosthetics that mimic or assist brain functions for patients with neurological and de

Series CDeveloper Tools
Series C$120.0M
Amplyx Pharmaceuticals
San Diego, CA · 31 employees

Amplyx Pharmaceuticals; Inc. is a preclinical stage company focusing on the development of small molecule drugs.

Series CBiology
$3.7M
VIRTUAL DENTAL CARE, INC.
Irvine, CA · Founded 2017

VIRTUAL DENTAL CARE; INC. is an Irvine; California-based company founded in 2017.

Healthtech
$52.0M
Medsphere Systems Corporation
Carlsbad, CA · Founded 2002 · 351 employees

Medsphere supplies inpatient electronic health record software to hospitals and behavioural health facilities; alongside revenue cycle management; supply chain management and managed IT services.

Digital health
$127.6M
Omniome
San Diego, CA · Founded 2013 · 126 employees

Omniome is a San Diego-based company.

Consumer biotechnology
Series A$29.5M
Empirico Inc.
San Diego, CA · Founded 2017 · 31 employees

Empirico Inc. comprises of biologists; physicians; chemists; data scientists and drug developers whose focus is on transforming patients' lives with innovative therapies.

Series ABiotechnology
Series B$63.0M
Happiest Baby
Santa Monica, CA · Founded 2001 · 126 employees

A company developing science-based products and services for the health; safety and emotional well-being of children and parents.

Series BTechnology
Series A$51.3M
CLARIFY MEDICAL, INC.
San Diego, CA · Founded 2014

CLARIFY MEDICAL; INC. is a San Diego-based healthcare company.

Series AHealthcare
Series C$45.0M
Swift Health Systems dba INBRACE
Irvine, CA

Swift Health Systems dba INBRACE is an Irvine; California-based company.

Series CHealth technology
Series A$25.0M
SGI-DNA
San Diego, CA · Founded 2009

SGI-DNA is a synthetic biology company that is headquartered in La Jolla; California and was founded by Craig Venter in 2013.

Series AConsumer biotechnology
Series B$9.9M
Modulated Imaging, Inc.
Irvine, CA · Founded 2005

Modulated Imaging; Inc. is an Irvine; California-based company founded in 2005.

Series BHealthcare
Series B$15.6M
PetDesk
San Diego, CA · Founded 2013 · 176 employees

PetDesk sells practice software to veterinary clinics. It covers client communication and reminders; online booking; an integrated phone system; AI-generated clinical notes and marketing; and is aimed

Series BPet technology
Series A$37.0M
Roswell Biotechnologies
San Diego, CA · 31 employees

Roswell Biotechnologies is a molecular electronics company that transforms DNA sequencing with new molecular electronics sequencing platform.

Series AEngineering
Series A$120.0M
Mirum Therapeutics
San Diego, CA

Mirum Therapeutics is a San Diego-based company in the pharmaceutical industry.

Series APharmaceutical industry
Seed$2.9M
Capillary Biomedical
Irvine, CA · Founded 2014 · 31 employees

Capillary Biomedical is an Irvine; California-based diabetes mellitus company founded in 2014.

SeedDiabetes mellitus
$438.0M
Samumed
San Diego, CA · Founded 2008

Samumed is a biotechnology company focused on the medical research and development for tissue-level regeneration.

Consumer biotechnology
Seed$45.0M
Silverado
Irvine, CA · Founded 1996 · 3001 employees

Silverado is an Irvine; California-based company founded in 1996.

SeedHealthtech
$63.4M
Pfenex
San Diego, CA · Founded 2009 · 126 employees

Pfenex is a San Diego-based company founded in 2009.

Biotechnology
Series A$85.0M
Ansun BioPharma
San Diego, CA

Anti-virals

Series ABiotechnology
Series A$60.0M
Neurana Pharmaceuticals
San Diego, CA

Neurana Pharmaceuticals is a small Molecule.

Series ABiomedical engineering
Series C$79.0M
Synthorx
La Jolla, CA · Founded 1954 · 10001 employees

Synthetic biology company that created novel DNA base pairs and uses them to incorporate novel amino acids into proteins for potential therapeutics in areas of cancer and autoimmune disorders.

Series CCancer
$76.0M
Zensun
San Diego, CA · 126 employees

Biotechnology company based in San Diego.

Biology
$25.0M
PatientSafe Solutions
San Diego, CA · Founded 2002 · 126 employees

PatientSafe Solutions is a San Diego-based company founded in 2002.

Healthcare
Series C$67.6M
Axonics Modulation Technologies
Irvine, CA · Founded 2013 · 751 employees

Axonics Modulation Technologies is a sacral Neuromodulation Device founded in 2013.

Series CHealthcare
Seed$1.9M
Collectly
Pasadena, CA · Founded 2017 · 106 employees

Collectly is a medical debt collection company founded in 2017 by Levon Brutian.

SeedPayments
$3.7M
DeepRadiology Corp
Santa Monica, CA · Founded 2013 · 31 employees

DeepRadiology Corp is a medical artificial intelligence company.

Radiology
Series C$240.0M
Blueprint Medicines
San Diego, CA · Founded 2011 · 751 employees

Blueprint Medicines is a biotechnology company that is working to improve human health.

Series CTechnology
$5.0M
Masimo
Irvine, CA · Founded 1989 · 3001 employees

Masimo is a noninvasive patient monitoring founded in 1989 by Joe Kiani.

Wearable technology
$30.0M
ConcertoHealth
Irvine, CA

ConcertoHealth is an Irvine; California-based company.

Healthtech
Series C$34.5M
Avelas Biosciences
San Diego, CA · Founded 2009 · 31 employees

A company focused on developing products for oncology surgery and therapeutic intervention

Series CMedical diagnostics
Series A$13.6M
Bioniz
Irvine, CA

Bioniz is a multi-cytokine inhibitory therapeutics.

Series AEngineering
$111.0M
Thrive Market
Los Angeles, CA · Founded 2013 · 751 employees

Thrive Market is an online retailer with over 2;500 high-quality healthy foods; vitamins; home goods; and beauty supplies.

E-commerce
Series D$60.2M
Suneva Medical
San Diego, CA · Founded 2009 · 126 employees

Suneva Medical is an aesthetic Medicine founded in 2009.

Series DHealthcare
Series A$5.4M
Levyx, Inc.
Irvine, CA · Founded 2013 · 31 employees

Levyx provies an enterprise-class data management platform for a variety of big data applications.

Series AHealthcare
$32.0M
Biotheranostics
San Diego, CA · Founded 2008 · 126 employees

A biotechnology company developing molecular-based diagnostic; prognostic; and predictive medical tests designed to help healthcare practitioners treat cancer.

Therapeutics
Series E$43.0M
OmeCare
San Diego, CA · Founded 2008 · 126 employees

OTC Genetic Testing

Series EBiotechnology
Series B$80.1M
Alphaeon
Irvine, CA · Founded 2013 · 126 employees

Alphaeon is an Irvine; California-based healthcare company founded in 2013.

Series BHealthcare