Biotechnology & Life Sciences startups in Southern California
The life-science research base behind San Diego's and Los Angeles's biotech reputations: platforms, tools, diagnostics and therapeutics spun out of UCSD, Scripps, Caltech and UCLA.
Companies
Series A$85.0MAnti-virals
Series C$79.0MSynthetic biology company that created novel DNA base pairs and uses them to incorporate novel amino acids into proteins for potential therapeutics in areas of cancer and autoimmune disorders.
$76.0MBiotechnology company based in San Diego.
$32.0MEdico Genome was a company based in San Diego; California that sells a product for processing DNA sequencing data. The company was acquired by Illumina in May 2018.
Series C$240.0MBlueprint Medicines is a biotechnology company that is working to improve human health.
Series C$34.5MA company focused on developing products for oncology surgery and therapeutic intervention
$32.0MA biotechnology company developing molecular-based diagnostic; prognostic; and predictive medical tests designed to help healthcare practitioners treat cancer.
OTC Genetic Testing
Series C$152.2MCelladon is a biotechnology company that focuses in the development of molecular therapies to treat heart failure.
Seed$74.9MCombimatrix Molecular Diagnostics; Inc. is a company that is part of the Medical & Diagnostic Laboratories Industry.
Series C$37.4MSG Biofuels is a biotechnology company developing renewable fuels.
Series D$62.1MCrown Bioscience is a contract research organisation for drug discovery; best known for oncology models and also working in cardiovascular and metabolic disease; with sites across the United States; E
Series B$59.5MIgnyta is a company that combines medicine and biotechnology for the treatment of cancer and autoimmune diseases.
A company developing therapeutics for veterinary medicine
Series E$65.0MA biopharmaceutical company that develops therapeutics to treat depressive disorders
Series C$50.5MA company focused on the development proteomics
Series A$3.6MA biotechnology company developing cancer therapeutics based on antibodies
Series C$73.2MA life science devices company focused on the discovery and development of protein biomarkers as diagnostic tests
$4.3MGeneTex is a research Antibodies founded in 1997.
Series D$43.3MSotera Wireless is a medical device company engaged in the development of wireless vital signs monitoring devices.
CombiMatrix is an Irvine; California-based healthcare company developing products and service for drug development; genetic analysis and diagnostics.
$55.0MA company developing reagents for immunology; multicolor flow cytometry and biological system analysis
Femta Pharmaceuticals is a biotechnology company that develops protein therapeutics
$260.0MA company developing pharmaceutical and diagnostic products to help physicians personalize patient care
A biopharmaceutical company developing small molecule therapeutics for respiratory and inflammatory disorders
Series D$28.0MGenoptix is a Carlsbad; California-based medical diagnostics company offering next-generation sequencing for oncology founded in 1999 by Tina Nova.
Series G$1.19BShield AI is a defense-tech company building the world's best AI pilots and next-generation aircraft.
Series C$862.2MSKIMS is a solutions oriented brand creating the next generation of underwear, loungewear and shapewear.
$656.4MDeveloping the next generation of oncology therapies for patients.
Series C$271.2MNewlight | AirCarbon - a natural, carbon-negative, regenerative, ocean-degradable material that can replace plastic. Harnessing the technology in nature to improve the world.
Series B$134.0MPelage Pharmaceuticals, Inc. is developing regenerative medicines for hair loss, specifically PP405, a non-invasive, topically-applied small molecule solution that reactivates dormant hair follicles by targeting stem cells.
Series C$132.6MEndeavor BioMedicines is a clinical-stage biotechnology company developing transformational medicines for life-threatening diseases.
Series B$100.8MAutobahn aims to improve life health for people affected by CNS disorders by driving the regenerative power of the human body.
Series A$100.0MDigitalBridge is a leading global alternative asset manager dedicated to investing in next-generation digital infrastructure and GenerativeAI
Series A$63.3MCeleCor Therapeutics develops zalunfiban, an investigational next-generation GPIIb/IIIa platelet inhibitor designed for pre-hospital treatment of STEMI heart attacks.
Series A$60.8MVST BIO Corp is a biotechnology company developing first-in-class antibody drugs for the treatment of inflammatory and cardiovascular diseases, including stroke and acute myocardial infarction, as well as sepsis.
Series B$60.1MPlexium is a next-generation targeted protein degradation (TPD) company that discovers Monovalent Direct Degraders and Molecular Glues.
Series B$56.0MElectrochemical Additive Manufacturing Mass Production of Next Generation Components High-Resolution Metal 3D Printing at Scale Electrochemical Additive Manufacturing (ECAM) is... Read More
Series A$55.5MBig Shot Pictures is a next-generation studio building global franchises, founded by Brian Robbins.
Series A$48.2MDiscover how Immunis, a private biotechnology company is developing new secretome products for the treatment of age-related immune dysfunction
Series C$41.2MMovandi Corp develops next-generation mmWave solutions that power both terrestrial and non-terrestrial communications, advancing 5G, fixed wireless, and satellite networks worldwide.
Series B$35.5MSalted Inc. is a platform that builds national, digital-first restaurant brands with clean, craveable food designed for a new generation.
Series B$32.9MProtego Bio is a clinical-stage biotech developing first-in-class small molecule pharmacological chaperones for AL amyloidosis and other protein misfolding diseases.
Series B$27.5MSmartHealth Holdings, Inc. drives transformative innovation in healthcare diagnostics, including groundbreaking imaging systems for pathology, advanced vascular diagnostics, and oncology-focused solutions, notably with its pioneering MUSE technology for slide-free digital pathology.
$25.0MMesa Residential partners with market-leading property managers to grow for decades as a multigenerational platform with over 50 years of history building exceptional growth companies.
Series A$22.4MWelcome to VIAVIA! Redefining the fashion experience for a new generation // Enjoy free shipping and returns on all orders // New Designers and products dropping daily
Series C$20.6MCoast Energy partners with commercial property owners to convert underutilized spaces into revenue-generating energy assets. Zero capex solar, storage & microgrid solutions that increase NOI and future-proof your portfolio.
Series A$20.0MThinkBio.Ai is an AI-powered healthcare and life sciences solutions company, transforming complex data into actionable insights for better, faster decision-making.
Series A$19.5MRejuvenate Bio uses a gene therapy approach to treat chronic, age-related diseases by targeting the root causes of aging to create treatments for chronic conditions affecting both companion animals and humans.
Series B$18.5MPaulex Bio stands at the threshold of what could be a transformative breakthrough for type 1 and type 2 diabetes: beta cell regeneration through an oral medicine designed to eliminate the root cause of diabetes.
Series B$17.8MAthos Therapeutics Inc. is a clinical stage biotechnology company that pioneers the development of artificial intelligence-based Precision Therapeutics for patients with Inflammatory Bowel Disease and other inflammatory diseases.
Series A$16.3MTempo Therapeutics is a biotechnology and tissue engineering company based out of San Diego, CA specializing in speeding up patient recovery.
Seed$15.8MEggCo, Inc., operating as Sunnyside Egg Co., produces eggs from hens raised outdoors in mobile coops on fresh pastures, supplemented with certified organic feed without corn, soy, or flax, using regenerative practices.
Series B$15.6MPM Technologies Corp provides generator sales, installation, service, and maintenance for residential, commercial, and industrial customers, focusing on emergency power solutions.
Series A$14.0MIn only five minutes and a penny-sized patch, Mindera Health technology captures thousands of RNA transcripts. We enable scalable collection and analysis of individualized genetic information to provide actionable, data-driven decisions for patients, providers and payers.
Series C$10.5MGenerate more event revenue with Events.com. Sell tickets online, promote your events, find sponsors, and grow your event business.
$10.0MLearn how Genomic Life enhances health and well-being through genetic screenings, early detection, personalized cancer navigation, and ongoing support. Optimize employee benefits and create a healthier workforce.
Seed$10.0MEGB Ventures is a physician-led venture formation family office focused on creating, financing, and developing biotechnology companies built around clinically validated therapeutic opportunities.
Seed$9.0MGeneral Galactic builds advanced spacecraft for sustained maneuver and more time on-mission across the space domain
Seed$8.2MSLAM BioTherapeutics, Inc. is a biotech company developing first-in-class human antibody-drug conjugates (ADCs) and bispecific monoclonal antibodies targeting blood cancers.