Biotechnology & Life Sciences startups in Southern California

EpiPlex™ assay detects RNA modifications by proximity barcoding and short read RNA sequencing, revealing insights into gene regulation for disease research.

We are a pioneering biotechnology company dedicated to producing innovative solutions to treat traumatic nerve injury.

BioProtonics is a pioneering company focused on advancing diagnostic imaging through its Magnetic Resonance Histopathology (MRH) technology. MRH offers a non-invasive, high-resolution method for analyzing tissue microarchitecture during routine MRI scans. MRH

Distribution marketing for music, entertainment, gaming, and brands. The AI Engine for virality, generating millions of views monthly.

Oxen.ai provides an AI platform for creators and builders, offering tools to generate videos and images, brainstorm with LLMs, organize asset libraries, and deploy custom fine-tuned endpoints.

ORANGE COMET is a next-generation gaming and entertainment company creating immersive games in partnership with the biggest properties in the world.

Organ donation connects a community of people together in a way that nothing else can. At Lifeline of Ohio, our mission is to support and honor that community—including the generous donors who gave the gift of life and the thousands still waiting for a donation.

Automate compliance in life science regulated markets.

AcuraStem is a patient-based biotechnology company pioneering how treatments are developed for neurodegenerative diseases, including sporadic ALS and FTD, using its proprietary disease-modeling platform, iNeuroRx®.

Excellos Labs is a cell therapy CDMO offering apheresis collection, PBMC and leukopak processing, T/NK cell isolation, and cGMP manufacturing for biotech and pharma.

Slips is the next-generation peer-to-peer betting platform where players bet against each other — not the house. Offering Heads Up, Pools, Tourlays, and AI-Generated Predictions, Slips creates a social-first experience where users win, connect, and compete in real time.

Transposon Therapeutics, Inc. is developing TPN-101 (also known as Censavudine) and other LINE-1 reverse transcriptase inhibitors for the treatment of rare neurodegenerative diseases such as progressive supranuclear palsy (PSP), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD).

XiltriX provides 24/7 live agent monitoring for biotech and biopharma labs and facilities that need to prevent sample loss and maintain compliance.

Resolute Science, Inc. is a biotechnology company developing a pipeline of first-in-class synthetic drug conjugates, specifically Macrophage-Targeted Conjugates (MAC-TACs), for the treatment of solid tumors.

Vesica Health, Inc. brings clarity to clinical decisions by combining next-generation molecular diagnostics and Blue Light Cystoscopy to improve early detection and diagnosis for bladder cancer patients, and offers the noninvasive urine-based AssureMDx test to identify hematuria patients at increased risk for bladder cancer.

NeuraNova's mission is to revolutionize neurovascular diagnostics to respond rapidly to critical moments.

Acurion's OncoGaze™ technology delivers critical genomic insights at the biopsy stage, empowering oncologists to make precision therapy a reality for more patients.

LaunchPoint Electric Propulsion Solutions is a propulsion and power generation company supplying lightweight, highly efficient, power-dense, electric and hybrid systems for aerospace, defense, unmanned aircraft systems, and advanced air mobility.

Why Use the Virchow Medical Crow’s Nest Biopsy Catchment System? To Improve Core Needle Biopsy Collection, Tissue Management, and Access to Targeted Diagnostics.

ChromaCode is a leading provider of HDPCR™ multiplexing technology for genomic solutions. Our breakthrough platform enables labs, physicians, and patients to access actionable biomarkers faster and more affordably. With HDPCR™, you can get critical and complete data, analyzed with simplicity, without paying for excess information.

2A Biosciences is pioneering neural restoration by advancing precision agonists to restore neural circuitry and immune balance, having demonstrated in vivo nerve regeneration via 5-HT2A modulation.

Aervivo enables our Partners to provide community wide Gigabit managed WiFi, delighting the communities they serve and generating an outstanding 100%+ IRR, quickly.

The majority of molecules sequenced are uninformative. Jumpcode Genomics is changing that by helping researchers boost usable NGS data.

Amydis is the leader in developing a new class of diagnostic compounds that enable digital detection and monitoring of human disease-related molecular biomarkers through standard ocular imaging cameras.

Telesair, Inc. is a non-invasive ventilation manufacturer. We enable respiratory care in any setting through high-flow oxygen generation and portability.

Professional AI voice generator for real production workflows, with free testing and flexible integration for studios and media teams.

Eco-luxury clothing from regenerative materials. TreeSilk TENCEL-blend, GOTS organic cotton, European Flax. Made in LA. Every purchase plants a tree.

Transforming medicine through cellular therapies that restore, regenerate, and repair tissues and organs

AscentX Medical, Inc. is dedicated to improving quality of life through injectable regenerative therapy focusing on advanced soft tissue engineering using autologous tissue engineering technology with injectable microspheres.

CancerVax is a pre-clinical biotech company developing a novel Universal Cancer Treatment Platform that uses artificial intelligence to disguise cancer cells to look like measles, thereby tricking the body's immune system into killing them.

NEXT-TFX is pioneering the next generation of ultra-high-pressure reverse osmosis (UHPRO) membranes to transform how industries manage water and extract valuable resources.

Navega Therapeutics is harnessing the precision of zinc-finger and CRISPR based epigenome regulation to enable next-generation gene therapies for chronic pain and precision pain management.

Yatiri Bio, Inc. is re-enisioning the pharmaceutical industry's current drug discovery process by integrating patient data sets with testable empirical models to guide patient selection and clinical development, utilizing advanced proteomics and bioinformatics tools and deep learning models.

BRT Biotechnologies provides high-quality macrocycle libraries using its proprietary BRiTeCycle® platform to advance drug discovery and enable rapid identification of promising drug leads for treating hard-to-drug targets.

Shreenika Pioneering Inc. creates high-performance, cost-effective chemicals through biotechnology for various industries, aiming to make sustainability an easy economic choice.

KAI Media is the Next Generation Fan-Centric Entertainment Company for All K-pop Fans Worldwide.

We are on a mission to change the path to power and influence in a tech-enabled world by launching a generation of diverse tech talent into the tech ecosystem.

Impulse Medical Technologies - A leading manufacturer and distributor of high-quality medical electrodes and diagnostic supplies. Parent company of The Electrode Store and TES Wholesale.

Abbott creates innovative medical devices and healthcare solutions for cardiovascular health, diabetes management, diagnostic testing, nutrition, chronic pain and more.

Mirae Creative is a small mobile app development shop with a live Google Play app, Quick Pass Generator.

Safeguard your digital memories with Kwillt. Securely store and share photos, videos, and stories with your family for generations.

World Tree grows Paulownia hardwood through regenerative forestry in partnership with farmers across the Americas.

Fabels Hospitality East, LLC, operating as GENUINE Hospitality, provides comprehensive hotel asset management for third-party ownership, focusing on revenue generation, operations, human resources, and finances.

Novella AI, Inc offers Ella, an AI Video Platform that allows creators to write, generate, and edit cinematic videos using AI models.

AI-enabled productivity and skill optimization for firms using Generative AI

LungLife AI is a diagnostic company focused on the early detection of lung cancer from a simple blood draw enhanced by artificial intelligence.

Renova Therapeutics is focused on developing definitive treatments to restore health to people suffering from congestive heart failure and type 2 diabetes through transformational gene therapies.

Harnessing Epigenetics to Improve Crops

Intrigue Health aims to empower patients and healthcare providers with home diagnostics.

For three generations, our family has pioneered the protection and restoration of our ocean. That’s why we founded SeaVoir – to create high quality ocean-derived products that support human health and ocean restoration.

MAPLE FUNG MD INC provides biotech consulting services, including fractional CMO roles and protocol design, and also offers per diem nephrology care and serves as a clinical trial investigator.

Phythera Therapeutics, Inc. is a biotechnology company leveraging the power of natural compounds to modulate key biological pathways in cancer and tissue regeneration to improve human health.

Revenue generation for live events

Genesis LA is a Community Development Financial Institution (CDFI) and Community Development Entity (CDE) that delivers financial solutions to advance economic and social opportunities in underserved communities in Los Angeles.

Condor is an AI-powered platform that unifies clinical, operational, and financial data into a single source of truth for life sciences companies to manage R&D finances.

MedicalMex helps and protects international patients traveling to Mexico for affordable medical services, including weight loss surgery, plastic surgery, pain management, hair restoration, dental, vascular, more procedures, orthopedic surgery, and general surgery.

Novoron Bioscience is pioneering lipoprotein-receptor drug development to repair damage and degeneration of the brain, spinal cord, and beyond, with therapies to block the spread of prion-like proteins and enhance spinal cord regeneration.

Kenai Therapeutics is a clinical-stage biotechnology company advancing off-the-shelf dopamine neuron replacement cell therapies and gene-modified medicines to cure neurological conditions.

Sylmar Group provides best-in-class people, technology, and service across industrial water treatment and well and pump maintenance to solve generational challenges of declining water availability and quality.

Ambros Therapeutics is a clinical-stage biotechnology company focused on developing innovative and transformative medicines for diseases with a high unmet medical need, with its lead investigational program targeting complex regional pain syndrome type 1 (CRPS-1).