Healthcare startups in La Jolla. Health tech, medical devices, and healthcare services, backed by a decades-old biotech research base and a deep bench of clinical and diagnostics startups.
Anchored by our protein-engineering expertise and our proprietary single-domain antibody platform, we’ve developed a unique pipeline of therapeutic candidates.
Enlaza Therapeutics is pioneering the field of covalent biologics, developing a novel classes of protein therapeutics based on its proprietary War-Lock™ platform.
Founded and led by Dr. Quyen Nguyen, a UC San Diego head-and-neck surgeon named to Forbes' 50 Over 50 Innovation list.

SYLKE® Skin Closure is a sterile, single-use, silk fibroin mesh strip with a pressure-sensitive adhesive intended for topical skin closure and wound support. The device is used to hold together well-approximated skin edges of a wound, and to cover and protect the wound. Learn more at sylke.com.
Founded by Dr. Stella Sarraf; its ALS drug candidate SPG302 received an FDA-authorized expanded access program in 2025.

Paulex Bio stands at the threshold of what could be a transformative breakthrough for type 1 and type 2 diabetes: beta cell regeneration through an oral medicine designed to eliminate the root cause of diabetes.

Model Medicines engineers first-in-class small molecules against biological choke points, using AI to advance pipeline-in-a-pill therapeutics across high-impact diseases.
We explore the immense therapeutic opportunities to help those bound by autoimmune neuropsychiatric diseases.

Valora Therapeutics is developing AbLec™ multispecific antibodies and T-Lec™ T cell engagers — antibody-engineering platforms that decoy the glyco-immune checkpoint to create best-in-class therapeutics for cancer and autoimmune disease.
AeroRx Therapeutics is developing potential best-in-class nebulized combination therapies to improve COPD treatment.
Learn how Genomic Life enhances health and well-being through genetic screenings, early detection, personalized cancer navigation, and ongoing support. Optimize employee benefits and create a healthier workforce.

Impulse Medical Technologies - A leading manufacturer and distributor of high-quality medical electrodes and diagnostic supplies. Parent company of The Electrode Store and TES Wholesale.
GRI Bio is a publicly traded clinical-stage biopharmaceutical company (Nasdaq: GRI), led by CEO Marc Hertz, PhD.