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The VCs actually headquartered in SoCal

26 firms, hand-verified — thesis, stage focus, and check size, not just a name and a logo.

All investors

Seed, Series AEst. 2008

Crosscut Ventures

Los Angeles, CA

Frontier Tech

Invests in early-stage frontier technologies, hardware and software, at the intersection of technology and physical-world transformation — the most established seed-stage venture fund in LA, taking founders from Seed to Series A.

Seed, Series A

Mucker Capital

Santa Monica, CA

Generalist

Venture capital for founders building outside Silicon Valley — invests in Seed and Series A companies across the US, Canada, and beyond, pairing capital with hands-on operating expertise.

Seed, Early-stageEst. 2005

Okapi Venture Capital

Newport Beach, CA

Information TechnologyLife Sciences

A seed and early-stage venture capital firm focused on information technology and life science investments, closing its first fund in 2006 after a group of local Orange County business leaders committed to backing the vision.

Pre-Seed, Seed, Series A

Pismo Ventures

Irvine, CA

Industry agnostic

Invests in early-stage startups that are beyond ideation, have a committed team, and possess domain expertise. Syndicates with other investment groups and facilitates funding for pre-seed, seed, and Series A companies, alongside an advisory arm offering fractional C-suite and exit-planning services to more established businesses.

Seed

SeedFolio

San Diego, CA

Life SciencesBiotechMedTechCleanTech

Invests early into strong teams developing novel technology to conquer disease or clean the planet, targeting large opportunities with high reward/risk ratios via a rigorous, systematic sourcing and selection process.

Pre-Seed, Seed

Sunstone Management

Irvine, CA

A diversified private capital firm investing in early-stage technology entrepreneurs, built on three stated pillars: founder-focused capital and technical assistance, scalable modern technology across sectors, and financially, socially, and environmentally sustainable businesses.

Seed, Bridge, Early Series AEst. 1997

TCA Venture Group

Irvine, CA

Industry agnostic

Formerly Tech Coast Angels, a not-for-profit angel investment organization founded in 1997 backing companies with innovative, differentiated solutions across industries. Supports entrepreneurs through seed, bridge, and early A-round funding, with a stated priority on California-based founders, though roughly half of investments now go outside the region.

Pre-Seed, Seed

TenOneTen Ventures

Los Angeles, CA

B2B / Deep Tech

Invests early in technical teams transforming major industries — healthcare, logistics, real estate, and manufacturing — betting on technical founders solving critical problems in sectors facing both existential threats and major opportunities.

Check size

$500K–$5M (typical round size the firm participates in, not a per-check figure)

Pre-Seed, Seed, Growth

Upfront Ventures

Los Angeles, CA

Generalist

Comes in at the earliest stages — seed or even pre-seed — and stays with founders through growth via its own growth fund. Invests nationally and internationally for the right deal, with investment professionals in both LA and the Bay Area.

Pre-seed, Seed

Wedbush Ventures

Santa Monica, CA

Fintechcommerce and mediafuture of workhealthcare tech (software-core)

A pre-seed and seed fund backing "visionary problem solvers": execution-oriented founders with strong founder/market fit who take a user-centric approach to big, market-transforming problems, in industries that are in transition. Software must be a core part of the solution.