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AIRCRAFT, ENTERTAINMENT, AND EVERYTHING AFTER

Los Angeles

394
companies
$3.81B
total raised
B2B, Consumer, Industrials
top industries
Photo: Basil D Soufi · CC BY-SA 3.0

A bit of history

Aviation took root here in 1910, when Wilbur Wright's biplane demo at Dominguez Hills sparked a rush of aircraft builders to the region's clear, flyable skies. Donald Douglas set up shop in 1920, renting space in an old movie studio in Santa Monica, before Douglas Aircraft grew into one of the city's largest employers. A few miles away, North American Aviation's Inglewood plant turned out thousands of P-51 Mustangs during World War II. Los Angeles has been building aircraft and entertainment side by side for over a century.

Series B$134.0M
Pelage Pharmaceuticals, Inc.
Los Angeles, CA

Pelage raised a $120 million Series B co-led by ARCH Venture Partners and Google's venture arm GV, with GV's Cathy Friedman appointed board chair.

Series BHealthcare
$106.8M
RENOVARO INC.
Los Angeles, CA

Renovaro revolutionizes cancer and neurology care through early detection, drug discovery, and personalized treatments. AI-powered precision medicine.

Healthcare
Series F$98.3M
NEONC TECHNOLOGIES HOLDINGS, INC.
Los Angeles, CA · Founded 2023

NeOnc is a clinical-stage life sciences company developing a novel intranasal drug delivery system and platform technology to treat brain cancers and other central nervous system (CNS) diseases by bypassing the Blood-Brain Barrier (BBB).

Series FHealthcare
Series B$85.0M
Prenuvo, Inc.
Los Angeles, CA

Proactive health memberships combining Whole Body MRI, advanced blood biomarker testing, and ongoing clinical guidance—designed to help you track your health year over year.

Series BHealthcare
Series B$84.3M
Akido Labs
Los Angeles, CA · Founded 2014 · 1000 employees

Rebuilding healthcare with AI at the core

Y CombinatorSeries BHealthcare
Series B$20.6M
Pictor Labs, Inc.
Los Angeles, CA · Founded 2019

Pictor Labs is The Virtual Staining Company enabling digital pathology adoption through computational virtual staining technology that preserves tissue for comprehensive downstream analysis.

Series BHealthcare
Series B$15.2M
OutcomeMD, Inc.
Los Angeles, CA

The Data Intelligence Network for Healthcare OutcomeMD’s Patient Experience Data Network™ turns de-identified patient-reported outcome measures (PROMs) into act

Series BHealthcare
$4.9M
California Compounding Company, Inc.
Los Angeles, CA · Founded 2026

California Compounding is a trusted compounding partner for telehealth and clinics, offering office stock programs, prescriber portals, and scalable fulfillment.

Healthcare
Series A$4.2M
Synaptec Health Inc.
Los Angeles, CA · Founded 2020

AI-driven medical coding from Synaptec Health - a more accurate, secure, and comprehensive solution for all your medical coding needs.

Series AHealthcare
$3.5M
Kairos Pharma, LTD.
Los Angeles, CA

Kairos Pharma develops novel therapies to combat cancer drug resistance and restore immune response, advancing innovative treatments for cancer patients.

Healthcare
Series A$3.3M
MCH Ventures, Inc.
Los Angeles, CA

Does business as Mahmee, a maternal health startup co-founded by Melissa Hanna that raised $3M in seed funding from Mark Cuban and Serena Williams.

Series AHealthcare
Series A$3.0M
Amydis, Inc.
Los Angeles, CA

Amydis is the leader in developing a new class of diagnostic compounds that enable digital detection and monitoring of human disease-related molecular biomarkers through standard ocular imaging cameras.

Series AHealthcare
$2.5M
Sure Count Surgical, LLC
Los Angeles, CA

SureCount SmartTrays streamline surgical instrument management, reducing errors, speeding counts, and improving safety across OR and SPD teams.

Healthcare
Series D$2.2M
Varsity Emergency Care Holdings, LLC
Los Angeles, CA

This entity is tied to Emergency Care Partners, which is majority owned by private-equity firm Varsity Healthcare Partners and received a structured equity investment from MidOcean Partners in 2025.

Series DHealthcare
Seed$1.2M
Paralos Bioscience Inc.
Los Angeles, CA · Founded 2024

Paralos Bioscience, co-founded by Yanxi Yang, is developing a phage-drug conjugate platform targeting drug-resistant infections and has been backed by Carbon Silicon Ventures, Larta Institute, Incate, and UCLA's Magnify program.

SeedHealthcare
Seed$819K
BioSig Technologies, Inc.
Los Angeles, CA

BioSig Technologies (Nasdaq: BSGM), originally a medical-device company, pivoted into real-world-asset tokenization through a 2025 merger with Streamex Exchange, backed by mining financier Frank Giustra as a strategic advisor.

SeedHealthcare
Series B$300K
Alto Labs LLC
Los Angeles, CA · Founded 2023
Series BHealthcare
Series A$200K
Aisona Care Inc.
Los Angeles, CA · Founded 2026
Series AHealthcare
$35
Surebion, Inc.
Los Angeles, CA · Founded 2025

Founded by Dr. Susanne B. Nicholas, a UCLA nephrology professor, to commercialize kidney-disease research from her own lab.

Healthcare
Immix Biopharma, Inc.
Los Angeles, CA

Founded and led by Ilya Rachman, a physician-scientist and former UCLA clinical faculty member; the company trades publicly on Nasdaq under ticker IMMX.

Healthcare
AesculaTech
Los Angeles, CA · Founded 2017 · 6 employees

Responsive materials, better lives.

Y CombinatorHealthcare
Axle Health
Los Angeles, CA · Founded 2021 · 14 employees

Scheduling and workforce management SaaS for home healthcare providers

Y CombinatorHealthcare
Illuminant Surgical
Los Angeles, CA · Founded 2022 · 11 employees

A new way of seeing inside the human body.

Y CombinatorHealthcare
Scanbase
Los Angeles, CA · Founded 2022 · 10 employees

The API for Diagnostic Test Analysis (COVID-19, FLU, RSV, STD,…

Y CombinatorHealthcare
Flowly
Los Angeles, CA · Founded 2021 · 3 employees

Our mobile app reduces chronic pain for 100 million Americans.

Y CombinatorHealthcare
Serif Health
Los Angeles, CA · Founded 2022 · 20 employees

Healthcare Price Transparency APIs and Data Products

Y CombinatorHealthcare
Makani Science
Los Angeles, CA · Founded 2021 · 2 employees

Reinventing respiration monitoring

Y CombinatorHealthcare
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