We explore the immense therapeutic opportunities to help those bound by autoimmune neuropsychiatric diseases.
Arialys Therapeutics, Inc. has raised $14.8M in total funding. The most recent round was Seed.
Arialys Therapeutics, Inc. is headquartered in La Jolla, CA.
We explore the immense therapeutic opportunities to help those bound by autoimmune neuropsychiatric diseases.
Pathogenic autoantibodies (most commonly targeting the NMDA receptor) can attack the brain and drive severe neurological and psychiatric conditions such as encephalitis, schizophrenia, dementia, stroke, and cancer-related cognitive impairment, with treatment options currently limited.
Arialys is developing precision medicines, designed using structural analysis of autoantibody-NMDAR interactions, that specifically block the effect of these pathogenic autoantibodies in the brain.
The company describes its lead candidate ART5803 as the first precision medicine designed for autoimmune neuropsychiatric disease, and reports it has received FDA Rare Pediatric Disease Designation and FDA IND clearance for a randomized Phase 2 study.
Arialys Therapeutics, founded by Mitsuyuki Matsumoto, raised $58M in seed financing in 2023 with backing from Johnson & Johnson's venture arm (Johnson & Johnson Innovation/JJDC) and Alexandria Venture Investments.
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